TL Leunbach, P Johansen, SM Tanner… - Ugeskrift for …, 2011 - ncbi.nlm.nih.gov A 28 month-old boy was hospitalized with pallor and weight stagnation. He had macrocytic anaemia and pancytopenia due to cobalamin deficiency and a rare homozygous mutation in the intrinsic factor gene. His sister showed similar symptoms at the age of 15 months. The ...
T Storm, F Emma, PJ Verroust… - … England Journal of …, 2011 - Mass Medical Soc ... Imerslund–Gräsbeck syndrome, or megaloblastic anemia 1, is a rare autosomal recessive disorder characterized by selective intestinal malabsorption of intrinsicfactor–vitamin B 12 ; it is frequently accompanied by tubular proteinuria.1 The syndrome is caused by mutations in ... Cited by 2 - Related articles - All 2 versions
HI Kim, WJ Hyung, KJ Song, SH Choi… - Annals of Surgical …, 2011 - Springer ... of proximal gastric cancer and longer patient survival as a result of early detection and improved treatment protocols.3–5 The absorption of vitamin B12 begins with a release of intrinsicfactor from gastric parietal cells, which are located on the gastric body and fundus.6 Binding ... Cited by 2 - Related articles - All 2 versions
MV Bor, E Nexo - Vitamins in the Prevention of Human …, 2011 - books.google.com ... protects the vitamin from the acid surroundings in the stomach, but in the alkaline environment of intestine haptocorrin is degraded by pancreatic enzymes, and the vitamin liberated from food and that recycled through the bile is recognised by intrinsicfactor, a glycoprotein ... Related articles - All 2 versions
M Shevell, D Watkins… - The Causes of Epilepsy: …, 2011 - books.google.com ... offspring. The absorption of dietary cobalamin requires the produc- tion by gastric parietal cells of cobalamin specific intrinsicfactor (IF) that binds to cobalamin to form a cobalamin- intrinsicfactor (Cbl-IF) complex. Specific distal ... Related articles
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