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PSEUDOMARKER: A Powerful Program for Joint Linkage and/or Linkage Disequilibrium Analysis on Mixtures of Singletons and Related Individuals

T Hiekkalinna, AA Schäffer, B Lambert… - Human …, 2011 - content.karger.com
A decade ago, there was widespread enthusiasm for the prospects of genome-wide association
studies to identify common variants related to common chronic diseases using samples of unrelated
individuals from populations. Although technological advancements allow us to query ...

The General Concepts of Gene Mapping: Linkage, Association, Linkage Disequilibrium and Marker Maps

NM Laird… - The Fundamentals of Modern Statistical Genetics, 2011 - Springer
In the absence of genetic data at the molecular level, the results of heritability, aggregation
and/or segregation analysis provided the first hints about the presence of genetic effects
and, consequently, the existence of a disease gene. Without infor- mation on the etiology ...

mapping complex disease genes using linkage disequilibrium and genome-wide association scans

LJ Palmer, NJ Timpson, DM Evans… - An Introduction to …, 2011 - books.google.com
FOUR mapping complex disease genes using linkage disequilibrium and genome- wide association
scans Lyle J. Palmer, Nicholas J. Timpson, David M. Evans, George Davey Smith, Lon R. Cardon
Summary Remarkable advances have occurred recently in our ability to detect genetic ...
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Nucleotide diversity and linkage disequilibrium in Populus nigra cinnamyl alcohol dehydrogenase (CAD4) gene

F Marroni, S Pinosio, G Zaina, F Fogolari… - Tree Genetics & …, 2011 - Springer
Abstract Cinnamyl alcohol dehydrogenase (CAD) is involved in the biosynthesis of lignin, a component
of plant cell wall which negatively impacts paper pulp processing and biomass fermentation
to ethanol. Transgenic poplars with depressed CAD activity show structural alterations of ...
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HLA-A* 7401–Mediated Control of HIV Viremia Is Independent of Its Linkage Disequilibrium with HLA-B* 5703

PC Matthews, E Adland, J Listgarten… - The Journal of …, 2011 - Am Assoc Immnol
The potential contribution of HLA-A alleles to viremic control in chronic HIV type 1 (HIV-1) infection
has been relatively understudied compared with HLA-B. In these studies, we show that
HLA-A*7401 is associated with favorable viremic control in extended southern African ...
Cited by 2 - Related articles - All 3 versions

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