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[PDF] from hindawi.comS Shimoda, C Selmi… - 2012 - downloads.hindawi.com
... Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease recognized at histology as
chronic nonsuppurative destructive cholangitis with an autoimmune pathogenesis supported
by Th1 or Th17 cells producing IFN-γ or IL-17 [1, 2]. Several inflammatory cell populations ...
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[HTML] from nih.govM Toyoda-Akui, H Yokomori, F Kaneko… - … Journal of General …, 2011 - ncbi.nlm.nih.gov
... IgM. Liver biopsy showed submassive lobular necrosis, inflammation with broad
areas of parenchymal collapse, and chronic nonsuppurative destructive cholangitis.
The patient responded well to corticosteroid therapy. This ...
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AH Ali, E Sinakos, MG Silveira… - Journal of Clinical …, 2011 - journals.lww.com
... Primary biliary cirrhosis (PBC) or chronic nonsuppurative destructive cholangitis 1 is an
autoimmune chronic cholestatic liver disease characterized by ongoing inflammatory destruction
of the intralobular bile ducts leading to biliary cirrhosis with consequent complications such ...
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[PDF] from hindawi.comM Sasaki… - 2012 - downloads.hindawi.com
... Primary biliary cirrhosis (PBC) is characterized by antimitochondrial autoantibodies (AMAs) in
patients' sera and histologically by chronic nonsuppurative destructive cholangitis in small bile
ducts, eventually followed by extensive bile duct loss and biliary cirrhosis. ...
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M Tsuda, YM Ambrosini, W Zhang, GX Yang… - …, 2011 - Wiley Online Library
... destruction in PBC. We hypothesized that chronic antigen stimulation of CD8 + T cells alters
effector memory T cell (TEM) frequency and function similar to that seen with chronic viral
infections including failure to terminally differentiate and relative resistance to apoptosis. ...
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