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Road to clinical efficacy: challenges and novel strategies for antimicrobial peptide development

R Eckert - Future Microbiology, 2011 - Future Medicine
... Despite the urgent need for novel anti-infectives, the road to the clinic is difficult, even if a molecule
is cheap to produce and is readily bioavailable ... Narrow-spectrum AMPs, such ... Synthetic peptides
are 100–500-times more expensive than conventional small-molecule antibiotics. ...
Cited by 1 - Related articles - All 3 versions

Model-Based Medical Decision Support–A Road to Improved Diagnosis and Treatment?

S Andreassen, D Karbing, U Pielmeier… - 15th Nordic-Baltic …, 2011 - Springer
... Page 3. Model-Based Medical Decision Support – A Road to Improved Diagnosis and Treatment?
259 IFMBE Proceedings Vol. 34 A. Glucosafe ... A secondary problem is that many patients receive
treatment with broad- spectrum antibiotics, prone to promote bacterial resistance. ...
Related articles - All 2 versions

Prospective audit and feedback on antibiotic prescription in an adult hematology-oncology unit in Singapore

CL Yeo, DSG Chan, A Earnest, TS Wu… - European Journal of …, 2011 - Springer
... of Medicine, National University Health System, 1E Kent Ridge Road, NUHS Tower Block,
Singapore 119228, Singapore e-mail: liyang_hsu@yahoo.com Eur J Clin Microbiol Infect Dis
DOI 10.1007/s10096-011-1351-6 Page 2. Broad-spectrum antibiotics, including carbapenems ...

An observational study on bloodstream extended-spectrum beta-lactamase infection in critical care unit: Incidence, risk factors and its impact on outcome

P Nasa, D Juneja, O Singh, R Dang… - European Journal of …, 2011 - Elsevier
... a Department of Critical Care Medicine, Max Super Speciality Hospital, 1, Press Enclave Road,
Saket, New Delhi, 110017, India. ... The hospital has an antimicrobial policy of empirically using
broad spectrum antibiotics for specific infections like hospital or ventilator associated ...

Epidemiology of oral yeast colonization and infection in patients with hematological malignancies, head neck and solid tumors

S Schelenz, S Abdallah, G Gray… - Journal of Oral …, 2011 - Wiley Online Library
... Other risk factors including diabetes, broad spectrum antibiotics and corticosteroids have been
described to promote the development of this ... Correspondence: Silke Schelenz, Department of
Microbiology, Nor- folk and Norwich University Hospital, Bowthorpe Road, NR2 3TX ...
Cited by 5 - Related articles - All 5 versions

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