推荐同事 机构合作 中文 繁體中文 English 한국어 日本語 Português Español

美国ACCDON公司旗下品牌

021-33361733，021-33632861

chinasupport@letpub.com

登录 注册 新注册优惠

Age-Related Macular Degeneration and the Other Double Helix The Cogan Lecture

J Ambati - Investigative Ophthalmology & Visual Science, 2011 - ARVO
It is notable that the first human trials of siRNAs were conducted in the eye. siRNAs targeting
VEGF-A (bevasiranib) or one of its receptors VEGFR-1 (siRNA-027/AGN 211745) were tested
as intravitreously administered drug candidates in clinical trials in patients with CNV due ...
Related articles - All 2 versions

Human telomerase model shows the role of the TEN domain in advancing the double helix for the next polymerization step

[HTML] from nih.govK Steczkiewicz, MT Zimmermann… - Proceedings of the …, 2011 - National Acad Sciences
Telomerases constitute a group of specialized ribonucleoprotein enzymes that remediate chromosomal
shrinkage resulting from the “end-replication” problem. Defects in telomere length regulation
are associated with several diseases as well as with aging and cancer. Despite ...
Related articles - All 4 versions

… Complementary Double-Stranded Helical Oligomers through Chiral and Achiral Amidinium− Carboxylate Salt Bridges and Chiral Amplification in Their Double-Helix …

H Ito, M Ikeda, T Hasegawa… - Journal of the …, 2011 - ACS Publications
A series of complementary molecular strands from 2-mer to 5-mer that are composed of m-terphenyl
units bearing chiral/achiral amidine or achiral carboxyl groups linked via Pt(II) acetylide complexes
were synthesized by sequential stepwise reactions, and their chiroptical properties on the ...
Cited by 1 - Related articles - All 4 versions

Transition dynamics and selection of the distinct S-DNA and strand unpeeling modes of double helix overstretching

[HTML] from nih.govH Fu, H Chen, X Zhang, Y Qu… - Nucleic acids …, 2011 - Oxford Univ Press
Recent studies have revealed two distinct pathways for the DNA overstretching transition near
65 pN: 'unpeeling' of one strand from the other, and a transition from B-DNA to an elongated
double-stranded 'S-DNA' form. However, basic questions concerning the dynamics of ...
Cited by 1 - Related articles - All 5 versions

Sculpting chromatin beyond the double helix epigenetic control of skeletal myogenesis.

V Sartorelli… - Current topics in developmental biology, 2011 - ncbi.nlm.nih.gov
Satellite cells (SCs) are the main source of adult skeletal muscle stem cells responsible for muscle
growth and regeneration. By interpreting extracellular cues, developmental regulators control
quiescence, proliferation, and differentiation of SCs by influencing coordinate gene ...
Related articles - All 2 versions

联系我们 | 站点地图 | 友情链接 | 授权代理商 | 加入我们

© 2010-2024 中国: LetPub上海分公司    网站备案号：沪ICP备10217908号-1    沪公网安备号：31010402006960

增值电信业务经营许可证：沪B2-20211595

礼翰商务信息咨询（上海）有限公司      办公地址：上海市徐汇区漕溪北路88号圣爱大厦1803室

United States: Tel: 1-781-202-9968 Address: 400 5th Ave, Suite 530, Waltham, Massachusetts 02451