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Viral Kinetics of Genital Herpes: A Molecular Probe Into Host-Viral Interactions

TC Quinn - Journal of Infectious Diseases, 2011 - jid.oxfordjournals.org
Utilization of new technological advances in molecular biology have enabled investigators to
accurately measure the quantitative amount of viral nucleic acids produced within a host over
time, thereby enabling investigations into host-viral interactions. The initial development ...

Persistent genital herpes simplex virus-2 shedding years following the first clinical episode

W Phipps, M Saracino, A Magaret… - Journal of Infectious …, 2011 - jid.oxfordjournals.org
Results. Time since first genital herpes episode was significantly associated with reduced genital
shedding. Total HSV shedding occurred on 33.6% of days in participants <1 year, 20.6% in those
1–9 years, and 16.7% in those ≥10 years from first episode. Subclinical HSV shedding ...
Cited by 3 - Related articles - All 4 versions

Replication-Defective Herpes Simplex Virus Mutant Strains as Genital Herpes Vaccines and Vaccine Vectors

[PDF] from harvard.eduDM Knipe - Replicating Vaccines, 2011 - Springer
Abstract Viral vaccines have traditionally been live, attenuated viruses, or inacti- vated
virus/subunits. Herpes simplex virus (HSV) vaccine candidates based on inactivated viruses
or subunits have not been effective thus far. In addition, attenu- ation of HSV to make a ...
Related articles - All 3 versions

[HTML] Episodic Therapy for Genital Herpes in Sub-Saharan Africa: A Pooled Analysis from Three Randomized Controlled Trials

[HTML] from plos.orgHA Weiss, GP Bailey, S Phiri, G Gresenguet… - PloS one, 2011 - dx.plos.org
Pooled data were analysed to estimate the impact of acyclovir on the proportion of ulcers healed
seven days after randomisation by HIV/CD4 status, ulcer aetiology, size and duration before
presentation; and impact on lesional HIV-1. Risk ratios (RR) were estimated using ...
Cached

European guideline for the management of genital herpes, 2010

R Patel, S Alderson, A Geretti… - … journal of STD & …, 2011 - ijsa.rsmjournals.com
Evidence for this guideline was provided by review of the Medline/Pubmed, Embase,
Google, Cochrane Library and relevant guidelines up to September 2008. A Medline/Pubmed
and Embase search was carried out from January 1981 to September 2008, looking for ...
Related articles - All 4 versions

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