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The Structure of the Wobbly Nuclear Pore Complex

A Hoelz… - Annual Review of Biochemistry, 2011 - annualreviews.org
In eukaryotic cells, the spatial segregation of replication and transcription in the nucleus and
translation in the cytoplasm imposes the requirement of transporting thousands of macromolecules
between these two compartments. Nuclear pore complexes (NPCs) are the sole ...
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The Dbp5 cycle at the nuclear pore complex during mRNA export II: nucleotide cycling and mRNP remodeling by Dbp5 are controlled by Nup159 and Gle1

KN Noble, EJ Tran, AR Alcázar-Román… - Genes & …, 2011 - genesdev.cshlp.org
Essential messenger RNA (mRNA) export factors execute critical steps to mediate directional
transport through nuclear pore complexes (NPCs). At cytoplasmic NPC filaments, the ATPase
activity of DEAD-box protein Dbp5 is activated by inositol hexakisphosphate (IP 6 )-bound ...
Cited by 4 - Related articles - All 2 versions

Regulation of the Dbp5 ATPase cycle in mRNP remodeling at the nuclear pore: a lively new paradigm for DEAD-box proteins

S Ledoux… - Genes & Development, 2011 - genesdev.cshlp.org
Dbp5 is one of 25 DEAD-box RNA-dependent ATPases in budding yeast. One or more
DEAD-box proteins are associated with every major step of RNA processing (for recent
reviews, see Cordin et al. 2006; Jarmoskaite and Russell 2010). This family of proteins is ...
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[HTML] HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2

[HTML] from plos.orgKE Ocwieja, TL Brady, K Ronen, A Huegel… - PLoS pathogens, 2011 - dx.plos.org
HIV continues to be responsible for approximately two million deaths worldwide each year. As
part of the viral replication cycle, the viral cDNA is transported through the nuclear pore into the
nucleus where it integrates into the host cell genome. HIV integrates non-randomly, likely ...
Cited by 2 - Related articles - Cached - All 6 versions

P granules extend the nuclear pore complex environment in the C. elegans germ line

DL Updike, SJ Hachey, J Kreher… - The Journal of Cell …, 2011 - jcb.rupress.org
The immortal and totipotent properties of the germ line depend on determinants within the germ
plasm. A common characteristic of germ plasm across phyla is the presence of germ
granules, including P granules in Caenorhabditis elegans, which are typically associated ...
Cited by 2 - Related articles - All 3 versions

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