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Structural Basis of Defects in the Sacsin HEPN Domain Responsible for Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS)

G Kozlov, AY Denisov, M Girard, MJ Dicaire… - Journal of Biological …, 2011 - ASBMB
... The C terminus of the protein contains an HEPN (higher eukaryotes and prokaryotes
nucleotide-binding) domain of unknown function. Here, we determined the high-resolution
1.9-Å crystal structure of the HEPN domain from human sacsin. ...
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Genetic and Molecular Basis of Inflammasome-mediated Disease

HM Hoffman… - Journal of Biological Chemistry, 2011 - ASBMB
... Dozens of novel intracellular protein candidates were identified, and this family
became collectively known as NLR, for nucleotide-binding domain (NBD) and
leucine-rich repeats (LRRs). NLR proteins have a central NBD (also ...
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Genotyping of the protozoan pathogen Toxoplasma gondii using high-resolution melting analysis of the repeated B1 gene

JM Costa, O Cabaret, S Moukoury… - Journal of Microbiological …, 2011 - Elsevier
... SNPs 94+114 SNP 366 SNP 754 SNP 1434 SNP 1558 SNP 1586 SNP 1992 HRM SNAP 94
SNAP 114 HRM SNAP HRM SNAP HRM SNAP HRM SNAP HRM SNAP HRM SNAP Strain Group
N ucleotide A/T Ratio N ucleotide G/A Ratio Group N ucleotide T/C Ratio Group N ...
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Structure and function of mammalian DNA methyltransferases

RZ Jurkowska, TP Jurkowski… - Chembiochem, 2011 - Wiley Online Library
... The general base involved in the proton abstraction is not known; involvement of a water molecule
or one of the RXR arginine residues has been discussed. 4. Dnmt1 (DNA nucleotide
methyltransferase 1). ... 5. Dnmt3 (DNA nucleotide methyltransferase 3) enzymes. ...
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Morphine Inhibits Murine Dendritic Cell IL-23 Production by Modulating Toll-like Receptor 2 and Nod2 Signaling

J Wang, J Ma, R Charboneau, R Barke… - Journal of Biological …, 2011 - ASBMB
... into the lungs. Dendritic cells and alveolar macrophages express various pattern
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Structural Basis of Defects in the Sacsin HEPN Domain Responsible for Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS)

Genetic and Molecular Basis of Inflammasome-mediated Disease

Genotyping of the protozoan pathogen Toxoplasma gondii using high-resolution melting analysis of the repeated B1 gene

Structure and function of mammalian DNA methyltransferases

Morphine Inhibits Murine Dendritic Cell IL-23 Production by Modulating Toll-like Receptor 2 and Nod2 Signaling