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In vitro evaluation of (S)-ibuprofen toxicity on joint cells and explants of cartilage and synovial membrane

L Bédouet, F Pascale, M Bonneau, M Wassef… - Toxicology in Vitro, 2011 - Elsevier
Intra-articular drug delivery systems (DDS) are envisaged as interesting alternative to locally
release nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen to reduce pain in patients
with osteoarthritis. The present study examines the toxicity of (S)-ibuprofen on ...

Reduction of in vitro invasion and in vivo cartilage degradation in a SCID mouse model by loss of function of the fibrinolytic system of Rheumatoid Arthritis synovial …

S Serratì, F Margheri, A Chillà… - Arthritis & …, 2011 - Wiley Online Library
... 28. Lefèvre S, Knedla A, Tennie C, Kampmann A, Wunrau C, Dinser R, et al. Synovial fibroblasts
spread rheumatoid arthritis to unaffected joints. Nat Med. 2009;15:1414-20 29. Hamilton JA and
Slyvka J. Stimulation of human synovial fibroblast plasminogen activator ...
Related articles - All 2 versions

CT and MR findings in synovial chondromatosis of the temporo-mandibular joint: Our experience and review of literature

L Testaverde, A Perrone, L Caporali… - European Journal of …, 2011 - Elsevier
Eight patients with symptoms and signs compatible with dysfunctional disorders of the TMJ underwent
CT and MR scan. We considered the following parameters: soft tissue involvement (disk
included), osteostructural alterations of the joints, loose bodies and intra-articular fluid. ...
Related articles - All 3 versions

'Alarmins' S100A8 and A9 determine synovial activation and joint destruction during experimental osteoarthritis

P van Lent, AB Blom, R Schelbergen… - Annals of the …, 2011 - ard.bmj.com
Methods Experimental OA was either induced by transection of the medial anterior meniscotibial
ligament which leads to destabilisation of the medial meniscus (DMM) or by injection of collagenase
into murine knee joints, which causes overall ligament damage and broad instability. ...

Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee.

JS Lewis, WC Hembree, BD Furman… - … and cartilage/OARS, …, 2011 - ncbi.nlm.nih.gov
OBJECTIVE: Post-traumatic arthritis is a frequent cause of disability and occurs most commonly
and predictably after articular fracture. The objective of this investigation was to examine the
effect of fracture severity on acute joint pathology in a novel murine model of ...
All 2 versions

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