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The role of stem cell factor and c-KIT in keloid pathogenesis: do tyrosine kinase inhibitors have a potential therapeutic role?

A Mukhopadhyay, DV Do, CT Ong… - British journal of …, 2011 - cat.inist.fr
Background Keloids are fibroproliferative disorders characterized by increased deposition of
extracellular matrix components. Stem cell factor (SCF) and its receptor c-KIT are expressed
in a wide variety of cells and have also been demonstrated to be important modulators of ...
Cited by 1 - Related articles

Inhibitory Activities of Omega-3 Fatty Acids and Traditional African Remedies on Keloid Fibroblasts

[PDF] from woundsresearch.comPB Olaitan, IP Chen, JEC Norris, R Feinn… - Wounds, 2011 - medscape.com
Keloids develop when scar tissue responds to skin trauma with proliferative fibrous growths that
extend beyond the boundaries of the original wound and progress for several months or
years. Keloids most frequently occur in individuals of indigenous sub-Saharan African ...
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Adenovirus-Mediated Human Interleukin 24 (MDA-7/IL-24) Selectively Suppresses Proliferation and Induces Apoptosis in Keloid Fibroblasts

J Liang, RL Huang, Q Huang, Z Peng… - Annals of Plastic …, 2011 - journals.lww.com
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Fussel-15, a New Player in Wound Healing, Is Deregulated in Keloid and Localized Scleroderma

S Arndt, J Schmidt, E Wacker, S Karrer… - The American Journal of …, 2011 - Elsevier
Dermal wound healing depends on highly complex interplay among various cytokines and cell
types. Disruption of this process can result in impaired healing in the form of excessive
scarring, as is the case in fibrotic diseases such as keloid and scleroderma. In the present ...
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[HTML] Heat Shock Proteins Modulate Keloid Formation

[HTML] from nih.govS Totan, A Echo… - Eplasty, 2011 - ncbi.nlm.nih.gov
Keloid scars represent an abnormal healing response in wounded tissue, which can create significant
distress for the patient. Keloids are most frequently seen between the first and third decades
of life and have a strong correlation with darkly pigment skin, which carries a 15- to ...
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