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A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition

FR Garcia-Gonzalo, KC Corbit, MS Sirerol-Piquer… - Nature Genetics, 2011 - nature.com
Mutations affecting ciliary components cause ciliopathies. As described here, we investigated
Tectonic1 (Tctn1), a regulator of mouse Hedgehog signaling, and found that it is essential for
ciliogenesis in some, but not all, tissues. Cell types that do not require Tctn1 for ...
Cited by 3 - All 3 versions

The Diagnostic Dilemma Of Primary Ciliary Dyskinesia: Findings And Experience Of The Genetic Disorders Of Mucociliary Clearance Consortium

MLA Daniels, B Baker, S Minnix, S Dell… - American Journal of …, 2011 - Am Thoracic Soc
A28 CILIA IN HEALTH AND DISEASE: PRIMARY CILIARY DYSKINESIA AND BRONCHIECTASIS
Sunday, May 15/8:15 AM-10:45 AM / Room 503-504 (Street Level), Colorado Convention Center
... The Diagnostic Dilemma Of Primary Ciliary Dyskinesia: Findings And Experience Of ...
All 3 versions

Ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for treatment of geographic atrophy in age-related macular degeneration

[PDF] from blind.isK Zhang, JJ Hopkins, JS Heier… - Proceedings of the …, 2011 - National Acad Sciences
There is no treatment available for vision loss associated with advanced dry age-related macular
degeneration (AMD) or geographic atrophy (GA). In a pilot, proof of concept phase 2 study, we
evaluated ciliary neurotrophic factor (CNTF) delivered via an intraocular encapsulated ...
Cited by 3 - Related articles - All 4 versions

Screening For Respiratory Ciliary Dysfunction In Autosomal Recessive Polycystic Kidney Disease

HB Root, M Gunay-Aygun… - American Journal of …, 2011 - Am Thoracic Soc
A28 CILIA IN HEALTH AND DISEASE: PRIMARY CILIARY DYSKINESIA AND BRONCHIECTASIS
Sunday, May 15/8:15 AM-10:45 AM / Room 503-504 (Street Level), Colorado Convention Center
... Screening For Respiratory Ciliary Dysfunction In Autosomal Recessive Polycystic ...
All 3 versions

MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis

CL Williams, C Li, K Kida, PN Inglis… - The Journal of Cell …, 2011 - jcb.rupress.org
Meckel-Gruber syndrome (MKS), nephronophthisis (NPHP), and related ciliopathies present
with overlapping phenotypes and display considerable allelism between at least twelve different
genes of largely unexplained function. We demonstrate that the conserved C. elegans B9 ...
Cited by 7 - Related articles - All 2 versions

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