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High T2 signal in primary lateral sclerosis supports the topographic distribution of fibers in the corpus callosum: assessing disease in the primary motor segment

SM Riad, H Hathout… - American Journal of …, 2011 - Am Soc Neuroradiology
PLS is a progressive pure UMN disorder first described in the late 1800s by Charcot and
Erb; it can be distinguished from ALS by its characteristic absence of LMN signs. Both conditions
arise sporadically, and both have been linked to specific mutations, 1 though PLS is far ...
Cited by 2 - Related articles - All 3 versions

44 Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis and Spinal Muscular Atrophy

MJ Strong, T Hortobágyi, K Okamoto… - … Molecular Pathology of …, 2011 - books.google.com
44 Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis and Spinal Muscular Atrophy Michael
J. Strong1, Tibor Hortobágyi2, Koichi Okamoto3 and Shinsuke Kato4 1 Canada Department
of Clinical Neurological Sciences, University ofWestern Ontario, and Robarts Research ...

Anti-Ma2/Ta antibodies in a woman with primary lateral sclerosis-like phenotype and Sjögren syndrome

G Piccolo, E Tavazzi, S Jarius, E Alfonsi… - Neurological …, 2011 - Springer
Abstract Anti-Ma2/Ta antibodies are rare paraneoplastic antibodies, which are mostly associated
with limbic encephalitis in male patients with testicular cancer. We report on a 50-year-old woman
with a pure progressive spastic paraparesis. Next, she was diagnosed as having a ...
Related articles - All 2 versions

Voxel-based diffusion tensor imaging detects pyramidal tract degeneration in primary lateral sclerosis

LC Tzarouchi, AP Kyritsis… - British Journal of …, 2011 - Br Inst Radiology
Objective: Primary lateral sclerosis (PLS) is a progressive degenerative disorder affecting upper
motor neurons and requires a clinical diagnosis. Diffusion tensor imaging (DTI) is a quantitative
method for assessing white matter fibre integrity. The purpose of the study was to ...
Related articles - All 3 versions

Direct evidence of intra-and interhemispheric corticomotor network degeneration in amyotrophic lateral sclerosis: An automated MRI structural connectivity study

S Rose, K Pannek, C Bell, F Baumann… - NeuroImage, 2011 - Elsevier
... Fifteen patients with probable or definite ALS as defined by the revised EL Escorial criteria (Brooks
et al., 2000) were recruited into the study, see Table 1. These patients were all typical ALS with
progressive muscular atrophy and primary lateral sclerosis variants excluded. ...

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