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Gimme Phospho-Serine Five! Capping Enzyme Guanylyltransferase Recognition of the RNA Polymerase II CTD

SK Burley… - Molecular Cell, 2011 - Elsevier
Capping of eukaryotic pre-mRNAs proceeds via a sequential three-step process, involving
(1) removal of the 5′ γ-phosphate group by an RNA triphosphatase (RTase), (2) addition of
GMP to the 5′ β-phosphate by a GTP-dependent guanylyltransferase (GTase), and (3) ...

Cap-binding Protein Complex Links Pre-mRNA Capping to Transcription Elongation and Alternative Splicing through Positive Transcription Elongation Factor b (P- …

T Lenasi, BM Peterlin… - Journal of Biological Chemistry, 2011 - ASBMB
Promoter-proximal pausing of RNAPII coincides with the formation of the cap structure at the
5′ end of pre-mRNA, which is bound by the cap-binding protein complex (CBC). Although the
positive transcription elongation factor b (P-TEFb) stimulates the release of RNAPII from ...
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Structure of the guanylyltransferase domain of human mRNA capping enzyme

[HTML] from nih.govC Chu, K Das, JR Tyminski… - Proceedings of the …, 2011 - National Acad Sciences
The enzyme guanylyltransferase (GTase) plays a central role in the three-step catalytic process
of adding an m7 GpppN cap cotranscriptionally to nascent mRNA (pre-mRNAs). The 5′-mRNA
capping process is functionally and evolutionarily conserved from unicellular organisms ...
Cited by 1 - Related articles - All 4 versions

CBC links pre-mRNA capping to transcription elongation and alternative splicing through P-TEFb

T Lenasi, BM Peterlin… - Journal of Biological Chemistry, 2011 - ASBMB
Promoter-proximal pausing of RNAPII coincides with the formation of the cap structure at the
5' end of pre-mRNA, which is bound by the cap-binding protein complex (CBC). Although the
P-TEFb elongation factor stimulates the release of RNAPII from pausing and promotes ...
Related articles - All 2 versions

Effects of Cu Self-Capping and Ta Capping on Nanometer-Sized Cu Films Sputter-Deposited on beta-Ta

H Tanimoto, T Sugimori, S Kumamoto, H Matsui… - Materials …, 2011 - jim.or.jp
The Cu(111) texture evolution in Cu films sputter-deposited on 35-nm β-Ta barrier layers on
Si(100) (Ta/Cu) and in those capped by 5-nm Ta (Ta/Cu/Ta) were studied by X-ray diffraction
(XRD). The Cu thicknesses (t Cu ) ranged from 5 to 500 nm. For Ta/Cu, the intensity of the ...
Related articles - Cached - All 3 versions

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