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A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12. 3

…, D Baris, M Thun, I De Vivo… - Human Molecular …, 2011 - Oxford Univ Press
Genome-wide and candidate-gene association studies of bladder cancer have identified 10
susceptibility loci thus far. We conducted a meta-analysis of two previously published
genome-wide scans (4501 cases and 6076 controls of European background) and ...

In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons

EA Thomas, G Coppola, B Tang… - Human molecular …, 2011 - Oxford Univ Press
Huntington's disease (HD), caused by a CAG repeat expansion in the huntingtin (HTT) gene,
is characterized by abnormal protein aggregates and motor and cognitive dysfunction. Htt protein
is ubiquitously expressed, but the striatal medium spiny neuron (MSN) is most susceptible ...
Cited by 2 - Related articles - All 5 versions

Foxp3+ regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2

[PDF] from utmb.eduY Chen, CJ Haines, I Gutcher, K Hochweller… - Immunity, 2011 - Elsevier
T helper 17 (Th17) cell development is driven by cytokines including transforming growth
factor-β (TGF-β), interleukin-6 (IL-6), IL-1, and IL-23. Regulatory T (Treg) cells can provide the
TGF-β in vitro, but their role in vivo remains unclear, particularly because Treg cells inhibit ...
Cited by 7 - Related articles - All 3 versions

Fluorescence imaging with one nanometer accuracy: in vitro and in vivo studies of molecular motors.

MT Hoffman, J Sheung… - Methods in molecular biology (Clifton, …, 2011 - Springer
Traditional microscopy techniques are limited by the wave-like characteristics of light, which
dictate that about 250 nm (or roughly half the wavelength of the light) is the smallest distance
by which two identical objects can be separated while still being able to distinguish ...

In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation

[PDF] from tufts.eduP Panizzi, M Nahrendorf, JL Figueiredo, J Panizzi… - Nature Medicine, 2011 - nature.com
Coagulase-positive Staphylococcus aureus (S. aureus) is the major causal pathogen of acute
endocarditis, a rapidly progressing, destructive infection of the heart valves. Bacterial colonization
occurs at sites of endothelial damage, where, together with fibrin and platelets, the ...

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