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A Randomized, Double-Blind Phase 2 Study Comparing the Efficacy and Safety of an Oral Fusidic Acid Loading-Dose Regimen to Oral Linezolid for the Treatment of …

JC Craft, SR Moriarty, K Clark… - Clinical Infectious …, 2011 - cid.oxfordjournals.org
Fusidic acid (CEM-102), an orally bioavailable fusidane antibiotic with a unique mode of
action, is under development for treatment of acute gram-positive bacterial skin and skin structure
infections, including those caused by methicillin-susceptible and methicillin-resistant ...
Cited by 1 - Related articles - All 2 versions

Comparison of Efficacy and Safety of a Standard Versus a Loading Dose of Clopidogrel for Acute Myocardial Infarction in Patients>= 75 Years of Age (from the FAST- …

E Puymirat, N Aīssaoui, P Coste, G Dentan… - The American Journal of …, 2011 - Elsevier
Data are lacking on the efficacy and safety of a loading dose (LD) of clopidogrel in elderly patients
with acute myocardial infarction (AMI). FAST-MI is a nationwide registry that was carried out over
a 1-month period in 2005 and included consecutive patients with AMI admitted to ...
Related articles - All 3 versions

High On-Treatment Platelet Reactivity After Prasugrel Loading Dose and Cardiovascular Events After Percutaneous Coronary Intervention in Acute Coronary …

L Bonello, M Pansieri, J Mancini… - Journal of the …, 2011 - Am Coll Cardio Found
Background: Post-treatment PR has been shown to be strongly associated with the occurrence
of major adverse cardiac events (MACE) after percutaneous coronary intervention (PCI) in the
clopidogrel era. Prasugrel is a new P2Y 12 –adenosine diphosphate receptor with a ...
Cited by 1

Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data

RMF van Schie, JAM Wessels… - European Heart …, 2011 - Eur Soc Cardiology
Methods and results In two Dutch anticoagulation clinics, data on age, sex, height, weight,
co-medication, coumarin derivative doses, and international normalized ratio values were obtained
from 624 patients taking PHE and 471 taking ACE. Single nucleotide polymorphisms ...
Cited by 1 - Related articles - All 2 versions

Impact of clopidogrel loading dose on clinical outcome in patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis

JM Siller-Matula, K Huber, G Christ, K Schrör… - Heart, 2011 - heart.bmj.com
Context Enhanced platelet inhibition by clopidogrel decreases the risk of ischemic events but
carries a risk for a concomitant increase in bleeding. ... Objectives To compare the efficacy and
safety of two clopidogrel loading regimens (300mg vs. 600mg) in patients undergoing ...
Cited by 8 - Related articles - All 4 versions

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