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Vancomycin Dosing: Assessment of Time to Therapeutic Concentration and Predictive Accuracy of Pharmacokinetic Modeling Software

MO Nunn, CE Corallo, C Aubron… - The Annals of …, 2011 - Harvey Whitney Books
... Results of Study Patients. In 51 patients (66.2%), initial dosing was compliant with
Australian guidelines; in this group, the initial vancomycin concentration was within
the therapeutic range in 15 (29.4%) patients. In 20 patients who ...
Cited by 2 - Related articles - All 3 versions

Bioanalytical Approaches to Quantify “Total” and “Free” Therapeutic Antibodies and Their Targets: Technical Challenges and PK/PD Applications Over the Course of …

JW Lee, M Kelley, LE King, J Yang… - The AAPS journal, 2011 - Springer
... “mAb” is defined as a monoclonal antibody therapeutic in the paper, “L” refers to the target ligand
in circulation. For simplicity, L is treated as monovalent ... Fig. 1. Effect of mAb–L affinity on mAbfree
over a range of molar ratios of mAb to L. The concentration of L was fixed at ...
Cited by 9 - Related articles - All 3 versions

The current role of liquid chromatography-tandem mass spectrometry in therapeutic drug monitoring of immunosuppressant and antiretroviral drugs

PJ Taylor, CH Tai, ME Franklin… - Clinical biochemistry, 2011 - Elsevier
... reported simultaneously measuring mycophenolic acid, mycophenolic acid glucuronide and
a range of glucocorticoids. ... everolimus, as these drugs are measured in whole blood and
therapeutic ranges have ... is its use in performing area under the blood concentration time curve ...
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Benzodiazepine Whole Blood Concentrations in Cases With Positive Oral Fluid On-Site Screening Test Results Using the DrugWipe Single for Benzodiazepines

T Blencowe, K Vimpari… - Journal of Analytical …, 2011 - ingentaconnect.com
... This means that in relation to the therapeutic concentration range for midazolam in plasma
(80–250 ng/mL) from the TIAFT website, the whole blood findings are all at a subther- apeutic
level: the equivalent plasma con- centrations are 8–79.5 ng/mL. ...
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[PDF] Rikkunshi-to Partially Reverses Cancer Chemotherapy-Induced Decrease in Plasma Valproic Acid Concentration in a Patient with Malignant Lymphoma

[PDF] from scirp.orgM Ishihara, K Kitaichi, K Matsuura, H Nakamura… - Chinese Medicine, 2011 - scirp.org
... 3. Results Before chemotherapy, plasma trough concentration of VPA was maintained within
a range of therapeutic concentration. ... 0 20 40 60 80 100 120 Therapeutic concentration range
Chemotherapy 1 Chemotherapy 2 Chemotherapy 1 Rikkunshi-to (7.5g/day) P las m a VP ...
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