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Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer

P Vainio, S Gupta, K Ketola, T Mirtti… - The American journal of …, 2011 - Elsevier
The arachidonic acid and prostaglandin pathway has been implicated in prostate
carcinogenesis, but comprehensive studies of the individual members in this key pathway are
lacking. Here, we first conducted a systematic bioinformatic study of the expression of 36 ...
Cited by 3 - Related articles - All 5 versions

Arachidonic Acid Metabolism and Lipid Peroxidation in Stroke: Alpha-Tocotrienol as a Unique Therapeutic Agent

C Rink, S Khanna… - Studies on Experimental Models, 2011 - Springer
Abstract Under normal physiological conditions, the human brain has one of the highest metabolic
profiles of all organs, using 25% of glucose and 20% of all oxygen consumed by the body. When
challenged by metabolic disruption as in ischemic or hemorrhagic stroke, brain tissue that ...
Related articles - All 2 versions

… LEFT VENTRICULAR DIASTOLIC FUNCTION IN HYPERTENSIVE PATIENTS WITH THE LOWER RATIO OF EICOSAPENTAENOIC ACID TO ARACHIDONIC ACID

H Ito, F Hayashi, K Nagao… - Journal of the …, 2011 - Am Coll Cardio Found
... Coll. Cardiol. Tanaka, Toshinori Makita, and Tsukasa Inada Yoshimasa Cyujyo, Yohei Kobayashi,
Michishige Ozeki, Koji Uchiyama, Masaru Haruyasu Ito, Fujio Hayashi, Kazuya Nagao, Kohei
Fukuchi, Motoko Tokunaga, ARACHIDONIC ACID WITH THE LOWER RATIO OF ...
All 2 versions

TRPV4 mediates tumor-derived endothelial cell migration via arachidonic acid-activated actin remodeling

AF Pla, HL Ong, KT Cheng, A Brossa, B Bussolati… - Oncogene, 2011 - nature.com
Changes in intracellular calcium [Ca 2+ ] i levels control critical cytosolic and nuclear events
that are involved in the initiation and progression of tumor angiogenesis in endothelial cells
(ECs). Therefore, the mechanism(s) involved in agonist-induced Ca 2+ i signaling is a ...
All 3 versions

Dietary Intakes of Arachidonic Acid and α-Linolenic Acid Are Associated with Reduced Risk of Hip Fracture in Older Adults

EK Farina, DP Kiel, R Roubenoff… - The Journal of …, 2011 - Am Soc Nutrition
PUFA are hypothesized to influence bone health, but longitudinal studies on hip fracture risk
are lacking. We examined associations between intakes of PUFA and fish, and hip fracture risk
among older adults (n = 904) in the Framingham Osteoporosis Study. Participants (mean ...
Related articles - All 3 versions

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