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Validation of isoleucine utilization targets in Plasmodium falciparum

[HTML] from pnas.orgES Istvan, NV Dharia, SE Bopp… - Proceedings of the …, 2011 - National Acad Sciences
Intraerythrocytic malaria parasites can obtain nearly their entire amino acid requirement by degrading
host cell hemoglobin. The sole exception is isoleucine, which is not present in adult human hemoglobin
and must be obtained exogenously. We evaluated two compounds for their potential to ...
Cited by 4 - Related articles - All 8 versions

Enantiomer elution order reversal of fluorenylmethoxycarbonyl-isoleucine in high-performance liquid chromatography by changing the mobile phase temperature and …

L Chankvetadze, N Ghibradze… - … of Chromatography A, 2011 - Elsevier
In this paper the elution order reversal of enantiomers of fluorenylmethoxycarbonyl-or
FMOC-isoleucine is described depending on the separation temperature and composition of
the mobile phase when using the polysaccharide-based chiral column Lux Cellulose-1 in ...

CK2 Phosphorylation of an Acidic Ser/Thr Di-isoleucine Motif in the Na+/H+ Exchanger NHE5 Isoform Promotes Association with β-Arrestin2 and Endocytosis

V Lukashova, EZ Szabó, T Jinadasa… - Journal of Biological …, 2011 - ASBMB
Internalization of the Na + /H + exchanger NHE5 into recycling endosomes is enhanced by the
endocytic adaptor proteins β-arrestin1 and -2, best known for their preferential recognition of
ligand-activated G protein-coupled receptors (GPCRs). However, the mechanism ...
Related articles - All 3 versions

Cytochrome P450 CYP94B3 mediates catabolism and inactivation of the plant hormone jasmonoyl-L-isoleucine

AJK Koo, TF Cooke… - Proceedings of the …, 2011 - National Acad Sciences
The phytohormone jasmonoyl-L-isoleucine (JA-Ile) signals through the COI1-JAZ coreceptor
complex to control key aspects of plant growth, development, and immune function. Despite detailed
knowledge of the JA-Ile biosynthetic pathway, little is known about the genetic basis of ...
Cited by 1 - Related articles - All 3 versions

… of amino acid biosynthesis in Xanthomonas campestris pv. campestris and identification of biosynthetic pathways for alanine, glycine, and isoleucine by 13 C- …

S Schatschneider, FJ Vorhölter, C Rückert… - Molecular Genetics and …, 2011 - Springer
Abstract To elucidate the biosynthetic pathways for all proteinogenic amino acids in Xanthomonas
campestris pv. campestris, this study combines results obtained by in silico genome analysis
and by 13C-NMR-based isotopologue profiling to provide a panoramic view on a ...

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