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Fibroblast growth factor signalling controls successive cell behaviours during mesoderm layer formation in Drosophila

IBN Clark, V Muha, A Klingseisen, M Leptin… - …, 2011 - dev.biologists.org
Fibroblast growth factor (FGF)-dependent epithelial-mesenchymal transitions and cell migration
contribute to the establishment of germ layers in vertebrates and other animals, but a comprehensive
demonstration of the cellular activities that FGF controls to mediate these events has not ...
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Voluntary Exercise Improves High-Fat Diet-Induced Leptin Resistance Independent of Adiposity

KAK Carhuatanta, G Demuro, MH Tschöp… - Endocrinology, 2011 - Endocrine Soc
The efficacy of exercise as primary prevention of obesity is the subject of intense
investigation. Here, we show that voluntary exercise in a mouse strain susceptible to diet-induced
obesity (C57B6J) decreases fat mass and increases energy expenditure. In addition, ...
Cited by 1 - Related articles - All 3 versions

Neuronal suppressor of cytokine signaling-3 deficiency enhances hypothalamic leptin-dependent phosphatidylinositol 3-kinase signaling

AS Metlakunta, M Sahu… - American Journal of …, 2011 - Am Physiological Soc
Suppressor of cytokine signaling-3 (SOCS3) is thought to be involved in the development of
central leptin resistance and obesity by inhibiting STAT3 pathway. Because phosphatidylinositol
3-kinase (PI3K) pathway plays an important role in transducing leptin action in the ...
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Leptin Grows Up and Gets a Neural Network

RD Cone… - Neuron, 2011 - Elsevier
The hypothalamus integrates sensory information with hormonal signals to regulate the activity
of the autonomic nervous system and control hormone secretion from the pituitary gland. The
organization and activity of hypothalamic neural circuits are critical for the integration of ...

Recombinant Human Leptin Treatment Does not Improve Insulin Action in Obese Subjects With Type 2 Diabetes

B Mittendorfer, JF Horowitz, AM DePaoli… - Diabetes, 2011 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS We conducted a randomized, placebo-controlled trial
in obese subjects (BMI: 35.4 ± 0.6 kg/m 2 ; mean ± SE) with newly diagnosed type 2
diabetes. Subjects were randomized to treatment with placebo (saline), low-dose (30 mg/ ...
All 3 versions

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