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Translational Control by the Eukaryotic Ribosome

I Topisirovic… - Cell, 2011 - Elsevier
In eukaryotes, during the initiation step of translation, 40S ribosomal subunits are recruited to
the mRNA by proteins known as translation initiation factors (Sonenberg and Hinnebusch,
2009). The 40S ribosome complex with associated factors navigates the mRNA 5′ ...
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[CITATION] Signaling Pathways that Mediate Translational Control of Ribosome Recruitment to mRNA

RJO Dowling… - Regulation of Organelle and Cell …, 2011 - Academic Press
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Response to Comment on “The Mechanism for Activation of GTP Hydrolysis on the Ribosome”

RM Voorhees, TM Schmeing, AC Kelley… - Science, 2011 - sciencemag.org
Our report of the crystal structure of elongation factor Tu (EF-Tu) and aminoacyl–transfer RNA
bound to the ribosome with a guanosine triphosphate (GTP) analog included a proposed mechanism
of GTP hydrolysis by EF-Tu involving histidine-84. Liljas et al. summarize experimental ...
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The ribosome and TORC2: collaborators for cell growth

X Xie… - Cell, 2011 - Elsevier
TOR is an atypical serine/threonine protein kinase conserved from yeast to mammals that forms
two distinct physical and functional complexes termed TORC1 and TORC2 (Figure 1) (Wullschleger
et al., 2006). TORC1, a rapamycin-sensitive complex, regulates translation, autophagy, ...
Cited by 1 - Related articles - All 2 versions

The ribosome uses two active mechanisms to unwind messenger RNA during translation

X Qu, JD Wen, L Lancaster, HF Noller… - Nature, 2011 - nature.com
The ribosome translates the genetic information encoded in messenger RNA into protein. Folded
structures in the coding region of an mRNA represent a kinetic barrier that lowers the peptide
elongation rate, as the ribosome must disrupt structures it encounters in the mRNA at its ...
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Translational Control by the Eukaryotic Ribosome

[CITATION] Signaling Pathways that Mediate Translational Control of Ribosome Recruitment to mRNA

Response to Comment on “The Mechanism for Activation of GTP Hydrolysis on the Ribosome”

The ribosome and TORC2: collaborators for cell growth

The ribosome uses two active mechanisms to unwind messenger RNA during translation