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R Agarwal, LA MacMillan-Crow, TM Rafferty… - … of Pharmacology and …, 2011 - ASPET
In overdose the analgesic/antipyretic acetaminophen (APAP) is hepatotoxic. Toxicity is mediated
by initial hepatic metabolism to N-acetyl-p-benzoquinone imine (NAPQI). After low doses NAPQI
is efficiently detoxified by GSH. However, in overdose GSH is depleted, NAPQI covalently ...
Cited by 1 - Related articles - All 3 versions
YW Chung, HK Kim, IY Kim, MB Yim… - Journal of Biological …, 2011 - ASBMB
12-O-tetradecanoylphorbol-13-acetate (TPA) has been shown to induce transcriptional activation
of human manganese superoxide dismutase (MnSOD) mRNA in human lung carcinoma
cells, A549, mediated by a protein kinase C (PKC)-dependent activation of cAMP- ...
HE Lob, A Vinh, L Li, Y Blinder, S Offermanns… - …, 2011 - ncbi.nlm.nih.gov
Previous studies indicate that superoxide is important in the modulation of blood pressure but
have not specifically identified the cell types or organs involved. We created mice with loxP sites
flanking the extracellular superoxide dismutase (SOD3) gene. These mice were crossed ...
All 2 versions
Z Van Rheen, C Fattman, S Domarski… - American journal of …, 2011 - ncbi.nlm.nih.gov
... 2011 Apr;44(4):500-8. Epub 2010 Jun 10. Lung extracellular superoxide dismutase
overexpression lessens bleomycin-induced pulmonary hypertension and vascular remodeling.
Van Rheen Z, Fattman C, Domarski S, Majka S, Klemm D, Stenmark KR, Nozik-Grayck E. ...
H Korekane, A Korekane, Y Yamaguchi… - Glycoconjugate …, 2011 - Springer
Abstract Extracellular superoxide dismutase (EC-SOD), the major SOD isoenzyme in biological
fluids, is known to be N-glycosylated and heterogeneous as was detected in most
glycoproteins. However, only one N-glycan structure has been reported in recombinant ...
Related articles - All 5 versions

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