推荐同事 机构合作 中文 繁體中文 English 한국어 日本語 Português Español

美国ACCDON公司旗下品牌

021-33361733，021-33632861

chinasupport@letpub.com

登录 注册 新注册优惠

A Multicellular Basis for the Origination of Blast Crisis in Chronic Myeloid Leukemia

RK Sachs, K Johnsson, P Hahnfeldt, J Luo, A Chen… - Cancer research, 2011 - AACR
Chronic myeloid leukemia (CML) is characterized by a specific chromosome translocation, and
its pathobiology is considered comparatively well understood. Thus, quantitative analysis of CML
and its progression to blast crisis may help elucidate general mechanisms of ...
Cited by 1 - Related articles - All 4 versions

Development of t (8; 21) and RUNX1-RUNX1T1 in the Philadelphia-positive clone of a patient with chronic myelogenous leukemia: additional evidence for multiple …

V Najfeld, N Wisch, J Mascarenhas, L Issa… - Cancer Genetics, 2011 - Elsevier
... Abbreviations: AML, acute myeloid leukemia; BC, blast crisis; CP, chronic phase; F, female; HU,
hydroxyurea; INFα, interferon α; M, male; NA, not available; Ph, Philadelphia chromosome; Tx,
treatment. a Interphase FISH showed >90% cells with BCR–ABL1 fusion. ...
Related articles - All 3 versions

… within BCR-ABL kinase domain confers imatinib resistance: sequential analysis of the clonal evolution in a patient with chronic myeloid leukemia in blast crisis

K Sakai, Y Ishikawa, Y Mori, M Kobayashi… - International journal of …, 2011 - Springer
Abstract BCR-ABL kinase domain mutations were sequentially analyzed in a patient with chronic
myeloid leukemia (CML) who exhibited repeated B-lymphoid blast crisis (CML-BC) during treatment
with imatinib and dasatinib. We first identified five mutant BCR-ABL clones: Y253H, ...
Cited by 1 - Related articles - All 3 versions

A deep-sequencing study of chronic myeloid leukemia patients in blast crisis (BC-CML) detects mutations in 76.9% of cases

V Grossmann, A Kohlmann, M Zenger, S Schindela… - Leukemia, 2011 - nature.com
Blast crisis (BC) is the terminal phase of chronic myeloid leukemia (CML) and is characterized
by a rapid expansion of myeloid or lymphoid differentiation-arrested blast cells leading to short
median survival. 1, 2 In approximately 70% of cases the blast lineage is myeloid, whereas ...
Cited by 1 - Related articles - All 4 versions

Graft-versus-Leukemia (GVL) against Mouse Blast-Crisis Chronic Myelogenous Leukemia (BC-CML) and Chronic-Phase Chronic Myelogenous Leukemia (CP-CML): …

C Matte-Martone, S Venkatesan… - The Journal of …, 2011 - Am Assoc Immnol
Graft-versus-leukemia (GVL) against chronic-phase chronic myelogenous leukemia
(CP-CML) is potent, but it is less efficacious against acute leukemias and blast-crisis chronic
myelogenous leukemia (BC-CML). The mechanisms underlying GVL resistance are ...

联系我们 | 站点地图 | 友情链接 | 授权代理商 | 加入我们

© 2010-2024 中国: LetPub上海分公司    网站备案号：沪ICP备10217908号-1    沪公网安备号：31010402006960

增值电信业务经营许可证：沪B2-20211595

礼翰商务信息咨询（上海）有限公司      办公地址：上海市徐汇区漕溪北路88号圣爱大厦1803室

United States: Tel: 1-781-202-9968 Address: 400 5th Ave, Suite 530, Waltham, Massachusetts 02451