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[PDF] from u-psud.frJP Guilloux, DJ David, L Xia, HT Nguyen… - …, 2011 - Elsevier
Selective serotonin (5-HT) re-uptake inhibitors (SSRIs) are commonly used in the treatment of
generalized anxiety disorder in Humans. However, because only few animal models display
overt anxious-like behavior, detailed preclinical studies of the anxiolytic properties of ...
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C Suzuki, C Miyamoto, T Furuyashiki, S Narumiya… - FEBS letters, 2011 - Elsevier
We found that centrally administered prostaglandin (PG) E 2 exhibited anxiolytic-like activity
in the elevated plus-maze and open field test in mice. Agonists selective for EP 1 and EP 4
receptors, among four receptor subtypes for PGE 2 , mimicked the anxiolytic-like activity of ...
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M Cazorla, J Prémont, A Mann… - The Journal of clinical …, 2011 - ncbi.nlm.nih.gov
The neurotrophin brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-related
kinase B (TrkB) have emerged as key mediators in the pathophysiology of several mood
disorders, including anxiety and depression. However, therapeutic compounds that ...
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Check for Full TextGV Carr, LE Schechter… - Psychopharmacology, 2011 - Springer
Abstract Rationale Although selective serotonin reuptake inhibitors (SSRIs) produce clinical
therapeutic effects on depression and anxiety through augmentation of serotonergic neuro-
transmission, there is little known about the potential contributions of the 5-HT6 receptor ...
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Check for Full TextS Gaburro, O Stiedl, P Giusti… - … scientific journal of …, 2011 - Cambridge Univ Press
Abstract Increasing evidence suggests that specific physiological measures may serve as biomarkers
for successful treatment to alleviate symptoms of pathological anxiety. Studies of autonomic function
investigating parameters such as heart rate (HR), HR variability and blood pressure (BP) ...
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