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… function six months post radiosurgery demonstrated normal cardiac function. Both animals met the survival endpoint with no adverse events. Conclusions: Cardiac …

PJ Maguire, E Gardner, AB Jack, P Zei… - Cardiac Radiosurgery …, 2011 - peeremed.com
Abstract: Abstract Objectives: This porcine pre-clinical investigation sought to demonstrate a
new and novel application for radiosurgery, the ablation of cardiac arrhythmias. Pre-clinical studies
in the porcine animal model were used to investigate the accuracy with which the ...
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Administration of Pigment Epithelium-Derived Factor Inhibits Left Ventricular Remodeling and Improves Cardiac Function in Rats with Acute Myocardial Infarction

S Ueda, S Yamagishi, T Matsui, Y Jinnouchi… - The American Journal of …, 2011 - Elsevier
Oxidative stress and inflammation are involved in cardiac remodeling after acute myocardial
infarction (AMI). We have found that pigment epithelium-derived factor (PEDF) inhibits vascular
inflammation through its anti-oxidative properties. However, effects of PEDF on cardiac ...
Cited by 1 - Related articles - All 4 versions

DOT1L regulates dystrophin expression and is critical for cardiac function

AT Nguyen, B Xiao, RL Neppl… - Genes & …, 2011 - genesdev.cshlp.org
Histone methylation plays an important role in regulating gene expression. One such methylation
occurs at Lys 79 of histone H3 (H3K79) and is catalyzed by the yeast DOT1 (disruptor of telomeric
silencing) and its mammalian homolog, DOT1L. Previous studies have demonstrated that ...
Cited by 4 - Related articles - All 2 versions

cGMP-PKG upregulates PGC1α and improves cardiac function in advanced cardiac hypertrophy independently of RGS2

E Takimoto - BMC Pharmacology, 2011 - biomedcentral.com
Impaired mitochondrial respiration was observed in advanced stage dilative 9wk TAC
hearts, associated with down-regulation of PGC1α, but not in 1-3 wk TAC hearts. Delayed sildenafil
treatment (100mg/kg/day) initiated after hypertrophy establishment (1-3 wk TAC) inhibited ...
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Quantification of left and right ventricular function and myocardial mass: Comparison of low-radiation dose 2nd generation dual-source CT and cardiac MRI

RAP Takx, A Moscariello, UJ Schoepf… - European Journal of …, 2011 - Elsevier
Twenty patients underwent 1.5 T cMRI and prospectively ECG-triggered dual-step pulsing cardiac
DSCT. This image acquisition mode performs low-radiation (20% tube current) imaging over
the majority of the cardiac cycle and applies full radiation only during a single adjustable ...

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