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Inhibitory Effect of Caffeic Acid on Human Organic Anion Transporters hOAT1 and hOAT3: A Novel Candidate for Food-drug Interaction.

Y Uwai, Y Ozeki, T Isaka, H Honjo… - Drug metabolism and …, 2011 - ncbi.nlm.nih.gov
Several kinds of food have been shown to influence the absorption and metabolism of
drugs, although there is little information about their effect on renal excretion of drugs. In this
study, we performed uptake experiments using Xenopus laevis oocytes to assess the ...

Evaluation of Warfarin Drug Interaction Listings in US Product Information for Warfarin and Interacting Drugs

D Ceron-Cabrera, K Romero, M Anthony… - …, 2011 - clinicaltherapeutics.com
« Previous Next » Clinical Therapeutics Volume 33, Issue 1 , Pages 36-45 , January 2011.
Evaluation of Warfarin Drug Interaction Listings in US Product Information for Warfarin and
Interacting Drugs. ... Concordance of severity ratings provided in four drug interaction compendia. ...
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How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins can be Applied for Evaluation of their Drug-Drug Interaction …

E Kraynov, SW Martin, S Hurst, OA Fahmi… - Drug Metabolism and …, 2011 - ASPET
... Therapeutic Proteins can be Applied for Evaluation of their Drug-Drug Interaction Potential ...
Abbreviations: TP, therapeutic protein; DDI, drug-drug interaction; P450, cytochrome P450; SM,
small molecule; mAb, monoclonal antibody; IFNα, interferon α; IFNα-2b, interferon α-2b; ...

Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line

M Hasegawa, Y Kapelyukh, H Tahara… - Molecular …, 2011 - ASPET
... 1 - Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated
drug-drug interaction in a novel multiple humanized mouse line ... 2 - Running title:
PXR/CYP3A4-mediated drug-drug interaction in humanized mice Address correspondence to: ...
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In silico prediction of efavirenz and rifampicin drug–drug interaction considering weight and CYP2B6 phenotype

D Rekić, D Röshammar, J Mukonzo… - British journal of …, 2011 - Wiley Online Library
• An example of utilization of in vitro data to predict in vivo consequences of metabolic drug–drug
interactions, suggesting answers to specific questions difficult to study in patients. Here the
efavirenz–rifampicin interaction was simulated with the specific question of whether or not ...
Cited by 1 - Related articles - All 4 versions

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