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Recessive Mutations in KCNJ13, Encoding an Inwardly Rectifying Potassium Channel Subunit, Cause Leber Congenital Amaurosis

…, AE Davidson, DS Mackay, Z Li, X Yang… - The American Journal of …, 2011 - Elsevier
... All have a distinct and unusual retinal appearance and a similar early onset of visual loss,
suggesting both impaired retinal development and progressive retinal degeneration, involving
both rod and cone pathways. Examination of heterozygotes revealed no ocular disease. ...

Alternative mitochondrial electron transfer as a novel strategy for neuroprotection

…, H She, Z Mao, JW Simpkins, SH Yang - Journal of Biological …, 2011 - ASBMB
... a novel strategy for neuroprotection against both chronic and acute neurological diseases
involving mitochondrial dysfunction ... the powerhouses and the major source of free radicals in
almost all cells ... diseases, including Parkinson disease (PD) 2 (1, 2), Alzheimer disease (AD) ( ...
Cited by 1 - Related articles - All 4 versions

Single-operator cholangioscopy in patients requiring evaluation of bile duct disease or therapy of biliary stones (with videos)

YK Chen, MA Parsi, KF Binmoeller… - Gastrointestinal …, 2011 - Elsevier
... in Figure 4. Because the analysis of sensitivity in intrinsic versus extrinsic disease was limited
to ... 6.1%) experienced 5 total serious ERCP- or SOC-related adverse events, all within the first ...
Involving 15 centers and 297 patients, this prospective study is the largest investigation of ...
Cited by 1

A hidden two-locus disease association pattern in genome-wide association studies

[PDF] from biomedcentral.comC Yang, X Wan, Q Yang, H Xue… - BMC …, 2011 - biomedcentral.com
... Instead, it is a genuine effect. Coronary artery disease (CAD) We identify four suspicious
associations involving five SNPs. The unadjusted P-values for these four ... involved in these five
associations indicate that they do not have noticeable marginal effects. All five SNPs ...
Related articles - All 5 versions

Treat Alzheimer's disease by traditional Chinese medicine?

MF Sun, TT Chang, KC Chen, SC Yang… - Molecular …, 2011 - Taylor & Francis
... View all references] to investigate TCM-based PDE4D inhibitors for Alzheimer's disease treatment
caused ... The SHAKE algorithm was used to fix all bonds involving hydrogen atoms ... Additionally,
all three TCM compounds were bound close to the active residue, His326, for cAMP ...

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