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Adenosine Enhances Endothelial Barrier Function Via Alteration Of Small Gtpases

Q Lu, J Newton, EO Harrington… - American Journal of …, 2011 - Am Thoracic Soc
... Adenosine Enhances Endothelial Barrier Function Via Alteration Of Small Gtpases , J. Newton ,
EO Harrington , S. Rounds Q. Lu1 1 1 1 ... We and others have shown that adenosine enhances
endothelial barrier function and protects against lung edema in acute lung injury (ALI). ...
All 3 versions

Angiopoietin-1 Requires IQ Domain GTPase-Activating Protein 1 to Activate Rac1 and Promote Endothelial Barrier Defense

S David, CC Ghosh, A Mukherjee… - … , and Vascular Biology, 2011 - Am Heart Assoc
Objective—IQ domain GTPase-activating protein 1 (IQGAP1) contributes to cytoskeletal network
regulation in epithelial cells by its scaffolding properties and by binding the Rho GTPase Rac1
to maintain its activity. The functions of IQGAP1 in endothelial cells beyond angiogenesis ...

Engaging neuroscience to advance translational research in brain barrier biology

EA Neuwelt, B Bauer, C Fahlke, G Fricker… - Nature Reviews …, 2011 - nature.com
The delivery of many potentially therapeutic and diagnostic compounds to specific areas of the
brain is restricted by brain barriers, of which the most well known are the blood–brain barrier
(BBB) and the blood–cerebrospinal fluid (CSF) barrier. Recent studies have shown ...
Cited by 4 - Related articles - All 6 versions

Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer

[PDF] from umaryland.eduA Fasano - Physiological Reviews, 2011 - Am Physiological Soc
The primary functions of the gastrointestinal tract have traditionally been perceived to be limited
to the digestion and absorption of nutrients and to electrolytes and water homeostasis. A more
attentive analysis of the anatomic and functional arrangement of the gastrointestinal tract, ...
Cited by 4 - Related articles - All 5 versions

Glucocorticoids Enhance Airway Epithelial Barrier Integrity

A Sekiyama, Y Gon, M Terakado… - American Journal of …, 2011 - Am Thoracic Soc
Asthma is a chronic inflammatory disorder of the airway. Glucocorticoids (GCs) are by far the
most effective anti-inflammatory therapy for asthma. Epithelial barrier damage is a cardinal feature
of chronic asthma. However, effect of GC on the airway epithelial barrier has not yet been ...
All 3 versions

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