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Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in liver

R Dentin, L Tomas-Cobos, F Foufelle, J Leopold… - Journal of …, 2011 - Elsevier
In liver, the glucose-responsive transcription factor ChREBP plays a critical role in converting
excess carbohydrates into triglycerides through de novo lipogenesis. Although the importance
of ChREBP in glucose sensing and hepatic energy utilization is strongly supported, the ...

O-GlcNAcylation Increases ChREBP Protein Content and Transcriptional Activity in the Liver

…, S Marmier, C Dubuquoy, R Dentin… - Diabetes, 2011 - Am Diabetes Assoc
OBJECTIVE Carbohydrate-responsive element–binding protein (ChREBP) is a key transcription
factor that mediates the effects of glucose on glycolytic and lipogenic genes in the liver. We have
previously reported that liver-specific inhibition of ChREBP prevents hepatic steatosis in ...
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The presence of the trans-10, cis-12 sequence does not have a body fat-lowering effect on jacaric acid, a conjugated linolenic acid isomer

…, I Churruca, J Ayo, C Garcia-Marzo, R Dentin… - Food Chemistry, 2011 - Elsevier
The term conjugated linolenic acid (CLNA) includes multiple positional and geometric cis and
trans isomers. The aim was to determine the potential effectiveness of jacaric acid, a CLNA
isomer, on body fat reduction in rats fed a high-fat diet, and its ability to activate the ...

Nano-layering of phosphoric-acid ester monomer at enamel and dentin

K Yoshihara, Y Yoshida, S Hayakawa, N Nagaoka… - Acta Biomaterialia, 2011 - Elsevier
Following the 'Adhesion-Decalcification' concept,specific functional monomers possess the capacity
to primary chemically interact with hydroxyapatite (HAp). Such ionicbondingwith synthetic HAp
has been demonstrated for 10-methacryloyloxydecyldihydrogenphosphate or 10-MDP to ...
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Hydrolytic Stability of One-step Self-etching Adhesives Bonded to Dentin.

A Fukuoka, K Koshiro, S Inoue… - The journal of …, 2011 - ncbi.nlm.nih.gov
Purpose: To evaluate the hydrolytic stability of three one-step self-etching adhesives
(1-SEAs) bonded to dentin through bond strength testing and ultra-morphological interfacial
analysis before and after long-term thermocycling. Materials and Methods: Eighteen ...