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W Tan, W Zhang, A Strasner, S Grivennikov… - Nature, 2011 - nature.com
Inflammatory mechanisms influence tumorigenesis and metastatic progression even in cancers
whose aetiology does not involve pre-existing inflammation or infection, such as breast and prostate
cancers 1 . For instance, prostate cancer metastasis is associated with the infiltration of ...
Cited by 12 - Related articles - All 4 versions
G Francia, W Cruz-Munoz, S Man, P Xu… - Nature Reviews …, 2011 - nature.com
An enduring problem in cancer research is the failure to reproduce highly encouraging preclinical
therapeutic findings using transplanted or spontaneous primary tumours in mice in clinical trials
of patients with advanced metastatic disease. There are several reasons for this, ...
Cited by 10 - Related articles - All 4 versions
EM Slorach, J Chou… - Genes & Development, 2011 - genesdev.cshlp.org
Amplification of 8p11-12 in human breast cancers is associated with increased proliferation and
tumor grade and reduced metastasis-free patient survival. We identified Zeppo1 (zinc finger
elbow-related proline domain protein 1) (FLJ14299/ZNF703) within this amplicon as a ...
Cited by 2 - Related articles - All 3 versions
[HTML] from pnas.orgS Hiratsuka, DG Duda, Y Huang… - Proceedings of the …, 2011 - National Acad Sciences
Increasing evidence suggests that myeloid bone marrow-derived cells (BMDCs) play a critical
role in lung metastasis. Blockade of VEGF receptor 1 (VEGFR1) has been proposed as a potential
strategy to limit myeloid BMDC recruitment to tumors. However, preclinical evidence ...
Cited by 4 - Related articles - All 5 versions
BZ Qian, J Li, H Zhang, T Kitamura, J Zhang… - Nature, 2011 - nature.com
Macrophages, which are abundant in the tumour microenvironment, enhance malignancy 1 .
At metastatic sites, a distinct population of metastasis-associated macrophages promotes the
extravasation, seeding and persistent growth of tumour cells 2 . Here we define the origin ...
Cited by 6 - Related articles - All 3 versions

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