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The Antiproliferative Action of Progesterone in Uterine Epithelium Is Mediated by Hand2

Q Li, A Kannan, FJ DeMayo, JP Lydon, PS Cooke… - Science, 2011 - sciencemag.org
... However, the mechanism for this is not clear. The attenuation of estrogen-mediated
proliferation of the uterine epithelium by progesterone is a prerequisite for successful
implantation. ... (a and b) Uterine sections obtained from day 4 pregnant mice. ...
Cited by 3 - Related articles - All 5 versions

A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids

PC Cha, A Takahashi, N Hosono, SK Low… - Nature Genetics, 2011 - nature.com
Uterine fibroids are a common benign tumor of the female genital tract. We conducted a
genome-wide association study in which 457,044 SNPs were analyzed in 1,607 individuals with
clinically diagnosed uterine fibroids and 1,428 female controls. SNPs showing suggestive ...
All 2 versions

Expression of the helicase‐like transcription factor and its variants during carcinogenesis of the uterine cervix: implications for tumour progression

A Capouillez, JC Noël, M Arafa, V Arcolia… - …, 2011 - Wiley Online Library
Here, we studied the immunohistochemical expression of HLTF in a series of 242 specimens
at different stages of cervical carcinogenesis. In normal exocervical specimens (20 cases), the
HLTF staining was weak and limited to basal or suprabasal areas (Figure 1C). In cervical ...
Related articles - All 2 versions

Reply to Lenz: Parental MHC disparity may affect offspring fitness via uterine natural killer cells

M Hemberger, A Moffett… - Proceedings of the …, 2011 - National Acad Sciences
NKRs can be inhibitory (iNKRs) or activating (aNKR). They are encoded by genes clustered
in two chromosomal regions in both humans and mice and, like MHC genes, are highly polymorphic
in both species. Our understanding of the outcome of NKR–MHC interactions is based on ...
Related articles - All 2 versions

Basement membrane sliding and targeted adhesion remodels tissue boundaries during uterine-vulval attachment in Caenorhabditis elegans

S Ihara, EJ Hagedorn, MA Morrissey, Q Chi… - Nature Cell …, 2011 - nature.com
Large gaps in basement membrane occur at sites of cell invasion and tissue remodelling in development
and cancer. Though never followed directly in vivo, basement membrane dissolution or reduced
synthesis have been postulated to create these gaps. Using landmark photobleaching ...
Cited by 1 - All 3 versions

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