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Inherited IgA glycosylation pattern in IgA nephropathy and HSP nephritis: where do we go next&quest

JK Boyd, J Barratt - Kidney International, 2011 - nature.com
New data from Kiryluk et al. show the importance of genetic factors in determining the profile
of serum IgA1 O-glycoforms in IgA nephropathy and Henoch–Schönlein purpura nephritis. Elevated
serum levels of poorly galactosylated IgA1 O-glycoforms do not, however, appear ...
All 2 versions

Development of autoimmune nephritis in genetically asplenic and splenectomized BAFF transgenic mice

CA Fletcher, JR Groom, B Woehl, H Leung… - Journal of …, 2011 - Elsevier
B cell activating factor belonging to the TNF family (BAFF or BLyS) is a critical B cell survival
factor essential for B cell maturation. BAFF transgenic (Tg) mice develop autoimmunity resembling
Systemic Lupus Erythematosus (SLE) in a T cell-independent but toll-like receptor (TLR) ...
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[HTML] Increased plasma levels of the soluble Mer tyrosine kinase receptor in systemic lupus erythematosus relate to disease activity and nephritis

[HTML] from arthritis-research.comJ Wu, C Ekman, A Jönsen… - Arthritis research & …, 2011 - arthritis-research.com
Mer and Tyro3 are receptor tyrosine kinases important for the phagocytosis of apoptotic
cells. Together with Axl, they constitute the TAM receptor family. These receptors can be shed
from the cell membrane and their soluble extracellular regions can be found in plasma. ...
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… Effects of PTK787/ZK222584, an Inhibitor of VEGFR and PDGFR [beta] Pathways, on Intussusceptive Angiogenesis and Glomerular Recovery from Thy1. 1 Nephritis

M Wnuk, R Hlushchuk, G Tuffin, U Huynh-Do… - The American Journal of …, 2011 - Elsevier
The aim of our study was to investigate the phenomenon of intussusceptive angiogenesis with
a focus on its molecular regulation by vascular endothelial growth factor receptor
(VEGFR)/platelet-derived growth factor receptor β (PDGFRβ) pathways and biological ...
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Complement factor H deficiency accelerates development of lupus nephritis

L Bao, M Haas… - Journal of the American Society of …, 2011 - Am Soc Nephrol
Complement factor H (CfH) is a key regulator of the alternative pathway, and its presence on
mouse platelets and podocytes allows the processing of immune complexes. Because of the
role of immune complexes in the pathophysiology of lupus nephritis, we studied the role ...
Cited by 1 - Related articles - All 4 versions

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