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Effect of Jiakang Pingxiao Pill on serum IL2/IL4 level in rat with Graves' disease

R CHEN, M ZHANG, Y BAI… - Chinese Traditional Patent …, 2011 - en.cnki.com.cn
... set up by injecting enterocolitis Yeersenshi fungus into caudalvein,and then we observed the
influence on GD rats'general condition,the change in its histomorphology and the level of blood
serum IL-2 and IL-4.RESULTS:Jiakang Pingxiao Pill combined Tapazole group could ...
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[PDF] Development of Postpartum Graves' Hyperthyroidism in a Woman with Hashimoto's Hypothyroidism

[PDF] from thyroidscience.comC Huang, D Fresca, D Jokic… - Thyroid, 2011 - thyroidscience.com
... 50 μg 8/06 (1st trimester) 98.070 0.97 50 μg 9/07 (6 months post partum) 4 0.049 10.44 73%
100 μg, off T and start Tapazole 10/07 < 0.01 2.02 Off Tapazole 11/07 < 0.01 1.03 357% 131RAI
therapy 2/7/08 15.38 0.94 50 μg 4/7/08 0.288 1.23 88 μg 7/14/08 0.228 1.33 88 μg 4 ...
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Liquid chromatography tandem mass spectrometry with ion trap and triple quadrupole analyzers for determination of thyreostatic drugs in urine and muscle tissue

B Wozniak, IM Zuchowska, J Zmudzki… - Analytica Chimica …, 2011 - Elsevier
... Liquid chromatography tandem mass spectrometry methods were developed and validated to
screen for and confirm residues of the thyreostatic drugs: tapazole, thiouracil, methylthiouracil,
propylthiouracil, and phenylthiouracil in bovine and porcine urine and muscle tissues ...
All 2 versions

The tissue-specific toxicity of methimazole in the mouse olfactory mucosa is partly mediated through target-tissue metabolic activation by CYP2A5

F Xie, X Zhou, MB Genter, M Behr, J Gu… - Drug Metabolism and …, 2011 - ASPET
... Methimazole (1-methyl-2-mercaptoimidazole; Tapazole) (MMZ), a drug commonly used for treating
hyperthyroidism, and also often used as a model substrate, as well as an inhibitor, for the
flavin-containing monooxygenases (FMO), is known to cause tissue-selective toxicity in ...
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Feed or Food Responsible for the Presence of Low-Level Thiouracil in Urine of Livestock and Humans?

JV Bussche, JAL Kiebooms, N De Clercq… - J. Agric. Food …, 2011 - ACS Publications
... 1) This goitrogenic activity may be attributed to the presence of a thiocarbamide group.(2) The
thyroid-inhibiting activity is in particular displayed by 2-thiouracil (TU), 6-methyl-2-thiouracil (MTU),
6-propyl-2-thiouracil (PTU), 1-methyl-2-mercaptoimidazole (TAP, tapazole), and 2 ...
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