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Protegen: a web-based protective antigen database and analysis system

[HTML] from nih.govB Yang, S Sayers, Z Xiang… - Nucleic Acids Research, 2011 - Oxford Univ Press
Protective antigens are specifically targeted by the acquired immune response of the host and
are able to induce protection in the host against infectious and non-infectious diseases. Protective
antigens play important roles in vaccine development, as biological markers for disease ...
Cited by 2 - Related articles - All 6 versions

Interactions of anthrax lethal factor with protective antigen defined by site-directed spin labeling

[HTML] from pnas.orgLD Jennings-Antipov, L Song… - Proceedings of the …, 2011 - National Acad Sciences
The protective antigen (PA) moiety of anthrax toxin forms oligomeric pores that translocate the
enzymatic moieties of the toxin—lethal factor (LF) and edema factor (EF)—across the endosomal
membrane of mammalian cells. Here we describe site-directed spin-labeling studies that ...
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Monoclonal antibodies directed against protective antigen of Bacillus anthracis enhance lethal toxin activity in vivo

SF Little, WM Webster… - FEMS Immunology & …, 2011 - Wiley Online Library
... 15 16 17 18 19 20 21 22 23 24 25 26 Monoclonal antibodies directed against protective antigen
of Bacillus anthracis enhance lethal toxin activity in vivo ... 9 10 11 12 13 14 15 16 17 Abstract
Protective antigen (PA) from Bacillus anthracis binds to cellular receptors, combines with ...
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[HTML] Dendritic Cells and Hepatocytes Use Distinct Pathways to Process Protective Antigen from Plasmodium in vivo

[HTML] from plos.orgIA Cockburn, SW Tse, AJ Radtke, P Srinivasan… - PLoS pathogens, 2011 - dx.plos.org
Malaria causes the deaths of 0.5–2 million people each year, mainly in Africa. A safe and effective
vaccine is likely needed for the control or eradication of this disease. Immunization by irradiated
malaria-infected mosquitoes has been shown to protect people against malaria. ...
Cited by 2 - Related articles - Cached - All 3 versions

Delayed treatment with W1-mAb, a chimpanzee-derived monoclonal antibody against protective antigen, reduces mortality from challenges with anthrax edema or …

L Altaweel, Z Chen, M Moayeri, X Cui… - Critical Care …, 2011 - journals.lww.com
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
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