推荐同事 机构合作 中文 繁體中文 English 한국어 日本語 Português Español

美国ACCDON公司旗下品牌

021-33361733，021-33632861

chinasupport@letpub.com

登录 注册 新注册优惠

[HTML] Resveratrol attenuates azidothymidine-induced cardiotoxicity by decreasing mitochondrial reactive oxygen species generation in human cardiomyocytes

[HTML] from nih.govRYUE GAO, P MUKHOPADHYAY… - Molecular medicine …, 2011 - ncbi.nlm.nih.gov
Nucleotide reverse transcriptase inhibitors, such as zidovudine (azidothymidine, AZT) and
stavudine, represent a class of approved antiretroviral agents for highly active antiretroviral
therapy, which prolongs the life expectancy of patients infected with human- ...
Related articles - All 2 versions

Corydaline Inhibits Multiple Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes

[PDF] from mdpi.comHY Ji, KH Liu, H Lee, SR Im, HJ Shim, M Son… - Molecules, 2011 - mdpi.com
... UGT1A4-mediated trifluoperazine N-glucuronidation and UGT2B7-mediated azidothymidine
glucuronidation were not inhibited by treatment with corydaline (Table 2). Corydaline inhibited
UGT1A1-catalyzed 17β-estradiol ... UGT2B7 Azidothymidine glucuronidation ...

Susceptibility of Primary HTLV-1 Isolates from Patients with HTLV-1-Associated Myelopathy to Reverse Transcriptase Inhibitors

[PDF] from mdpi.comB Macchi, E Balestrieri, A Ascolani, S Hilburn… - Viruses, 2011 - mdpi.com
... from patients with HTLV-1-associated myelopathy. Sensitivity to azidothymidine (AZT), lamivudine
(3TC), tenofovir (TDF) and three phosphonated carbocyclic 2‟-oxa-3‟aza nucleosides (PCOANs)
was assessed in a RT inhibitor assay. With the exception of 3TC, ...
Related articles - All 2 versions

The many faces of the adamantyl group in drug design

J Liu, D Obando, V Liao, T Lifa… - European journal of medicinal …, 2011 - Elsevier
... This concept is well illustrated in the case in which adamantyl-1-acetic acid was
appended via an ester bond to the AIDS drug azidothymidine to produce a prodrug
with improved carriage across the blood brain barrier. Intravenous ...
All 3 versions

Pentacycloundecane-based Inhibitors of Wild-type C-South African HIV Protease

MM Makatini, K Petzold, SN Sriharsha… - Bioorganic & medicinal …, 2011 - Elsevier
... Abbreviations: PIs, Protease inhibitors; HIV-PR, HIV protease; AZT, azidothymidine;
CNS, Central Nervous System; PCU, Pentacycloundecane. ... 8, 16, 17 Adamantane was
previously coupled to azidothymidine (AZT). 8, 18 Brookes et al. ...
All 3 versions

联系我们 | 站点地图 | 友情链接 | 授权代理商 | 加入我们

© 2010-2024 中国: LetPub上海分公司    网站备案号：沪ICP备10217908号-1    沪公网安备号：31010402006960

增值电信业务经营许可证：沪B2-20211595

礼翰商务信息咨询（上海）有限公司      办公地址：上海市徐汇区漕溪北路88号圣爱大厦1803室

United States: Tel: 1-781-202-9968 Address: 400 5th Ave, Suite 530, Waltham, Massachusetts 02451