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RAS signaling pathway mutations and hypertrophic cardiomyopathy: getting into and out of the thick of it

BD Gelb, M Tartaglia, C Boshoff… - The Journal of …, 2011 - Am Soc Clin Investig
In this issue of the JCI, Wu et al. and Marin et al. describe two new mouse models of inherited
disorders of the RAS/MAPK signal transduction pathway that display hypertrophic cardiomyopathy
(HCM); the model from the former paper was from a gain-of-function Raf1 mutation, and ...
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CARDIAC FUNCTION AND HEART FAILURE

MSINH CARDIOMYOPATHY - Journal of the American …, 2011 - Am Coll Cardio Found
... Background: Diastolic dysfunction is common in hypertrophic cardiomyopathy (HCM) patients. ...
The predominant HCM morphology was asymmetric septal hypertrophy with scar primarily found
in the septum of all patients in Group 2. Group 2 had significantly lower mean septal E ...
All 2 versions

… node tachycardia: beta-blocker or If-channel inhibitor? Implantable cardioverter-defibrillator therapy in patients with hypertrophic cardiomyopathy: is atrial fibrillation a …

H Tada, H Yamasaki, Y Sekiguchi… - …, 2011 - Eur Heart Rhythm Assoc

[HTML] Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome–associated PTPN11 mutation

[HTML] from nih.govTM Marin, K Keith, B Davies… - The Journal of clinical …, 2011 - ncbi.nlm.nih.gov
1 Department of Medicine, Division of Cardiology, Beth Israel Deaconess Medical Center,
Boston, Massachusetts, USA. 2 Department of Internal Medicine, School of Medicine, State University
of Campinas, Campinas, Brazil. 3 Department of Genetics and Howard Hughes Medical ...
Cited by 8 - Related articles - All 4 versions

PREVALENCE AND CLINICAL PROFILE OF MYOCARDIAL CRYPTS IN HYPERTROPHIC CARDIOMYOPATHY

MS Maron, E Rowin, D Lin… - Journal of the …, 2011 - Am Coll Cardio Found
... Background: In patients with hypertrophic cardiomyopathy (HCM), cardiovascular magnetic
resonance (CMR) can detect morphologic abnormalities of the ... in consecutive patients: 23 genotype
positive/phenotype negative HCM family members without LV hypertrophy (27±17 ...
All 2 versions

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