推荐同事 机构合作 中文 繁體中文 English 한국어 日本語 Português Español

美国ACCDON公司旗下品牌

021-33361733，021-33632861

chinasupport@letpub.com

登录 注册 新注册优惠

A Fission Yeast-Based Platform for Phosphodiesterase Inhibitor HTSs and Analyses of Phosphodiesterase Activity

D Demirbas, O Ceyhan, AR Wyman… - … as Drug Targets, 2011 - Springer
Abstract Fission yeast strains have been engineered so that their growth behavior reflects the
activity of heterologous cyclic nucleotide phosphodiesterases (PDEs). These strains can be used
in High-Throughput Screens (HTSs) for PDE inhibitors that possess “drug-like” ...
Related articles - All 2 versions

The Type 4 Phosphodiesterase Inhibitor Rolipram Ameliorates Chlorine-Induced Acute Lung Injury In Mice

GW Hoyle, W Chang, J Chen… - American Journal of …, 2011 - Am Thoracic Soc
... The Type 4 Phosphodiesterase Inhibitor Rolipram Ameliorates Chlorine-Induced
Acute Lung Injury In Mice , W ... Rolipram is an inhibitor of type 4 phosphodiesterase
and increases cAMP levels by inhibiting cAMP hydrolysis. The ...
All 3 versions

[HTML] Ibudilast, a Pharmacologic Phosphodiesterase Inhibitor, Prevents Human Immunodeficiency Virus-1 Tat-Mediated Activation of Microglial Cells

[HTML] from plos.orgM Kiebala… - PloS one, 2011 - dx.plos.org
Human Immunodeficiency Virus-1 (HIV-1)-associated neurocognitive disorders (HAND)
occur, in part, due to the inflammatory response to viral proteins, such as the HIV-1 transactivator
of transcription (Tat), in the central nervous system (CNS). Given the need for novel ...
Related articles - Cached - All 3 versions

[PDF] Application of adaptive design and decision making to a phase II trial of a phosphodiesterase inhibitor for the treatment of intermittent claudication

[PDF] from biomedcentral.comR Lewis, J Connor, J Teerlink, J Murphy, L Cooper… - Trials, 2011 - biomedcentral.com
Background: Claudication secondary to peripheral artery disease (PAD) is associated with substantial
functional impairment. Phosphodiesterase (PDE) inhibitors have been shown to increase walking
performance in these patients. K- 134 is a selective PDE 3 inhibitor being developed as a ...
Related articles - View as HTML - All 14 versions

Phosphodiesterase Inhibitor Effect on Small Artery Function in Preeclampsia

RA Samangaya, M Wareing… - Hypertension in …, 2011 - informahealthcare.com
Objective. To determine if the phosphodiesterase type 5 inhibitor, sildenafil citrate improves
endothelial-dependent relaxation of small arteries from women with preeclampsia. Methods.
Myometrial and omental biopsies were taken from women participating in a randomized ...
Related articles - All 3 versions

联系我们 | 站点地图 | 友情链接 | 授权代理商 | 加入我们

© 2010-2024 中国: LetPub上海分公司    网站备案号：沪ICP备10217908号-1    沪公网安备号：31010402006960

增值电信业务经营许可证：沪B2-20211595

礼翰商务信息咨询（上海）有限公司      办公地址：上海市徐汇区漕溪北路88号圣爱大厦1803室

United States: Tel: 1-781-202-9968 Address: 400 5th Ave, Suite 530, Waltham, Massachusetts 02451