SK Shenoy… - Trends in Pharmacological Sciences, 2011 - Elsevier ... planar cell polarity signaling [56]. Another atypical 7TMR that is regulated by β-arrestin is the Smoothened (Smo) receptor that transduces hedgehog (Hh) signaling, which is important for vertebrate development. β-Arrestin 2 is ... Related articles - All 2 versions
G El Akabawy, L Martinez-Medina… - Stem Cells and …, 2011 - liebertonline.com ... (paired box gene 6, PAX6) (Table 4 lists primer sequences). Action through Hedgehog pathway As purmorphamine is known to act through the smoothened (SMO) receptor on the ... By antagonising the SMOreceptor with KAAD-cyclopamine (3-keto-N-aminoethyl-N1- ... Related articles - All 3 versions
M Barzi, D Kostrz, A Menendez… - Journal of Biological Chemistry, 2011 - ASBMB ... Tel.: 34933632382; Fax: 34933638301; E-mail: spfnqi{at}iibb.csic.es. Next Section. Abstract. Proliferation of cerebellar granular neuronal precursors (CGNPs) is mediated by Sonic Hedgehog (Shh), which activates the Patched and Smoothened (Smo) receptor complex. ... Cited by 1 - Related articles - All 4 versions
T Tang, JY Tang, D Li, M Reich, CA Callahan… - Clinical Cancer …, 2011 - AACR ... BCCs commonly contain mutations that inactivate the patched 1 (PTCH1) receptor (4) or constitutively activate the Smoothened (SMO) receptor (7, 8). Both have the same functional consequence—ligand-independent, uncontrolled activation of the Hh signaling pathway. ... Related articles - All 3 versions
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