N SHIRAISHI, Y INAI, Y HIRANO… - Bioscience, Biotechnology, …, 2011 - J-STAGE ... in cattle, and kuru or Gerstmann– Straussler–Scheinker disease, fatal familial insomnia, Creutzfeldt–Jakob disease (CJD), and variant CJD in humans, are fatal neurodegenerative disorders associated with the conversion of PrPC into the infectious scrapieisoform (PrPSc).1 ...
AO Samson… - Biochemistry, 2011 - ACS Publications ... disease to structure have also been made through the identification of the minimal prion protein fragment that is capable of conferring propagation of the scrapie agent Page 4 of 27 ... understood and structures of the monomeric isoforms and oligomers are still unresolved. ... Related articles - All 3 versions
GS Baron, AG Hughson, GJ Raymond… - Biochemistry, 2011 - ACS Publications ... have made these analyses possible: (1) the recent availability of scrapie-infected transgenic mice expressing only anchorless PrP molecules that are also severely deficient in Asn-linked glycans (eg, see the predominance of the lower, unglycosylated isoform in panels A and B ... Cited by 2 - Related articles - All 2 versions
M Imamura, N Kato, M Yoshioka, H Okada… - Journal of …, 2011 - Am Soc Microbiol ... Chem. 285:14083-14087.[Abstract/Free Full Text]; 20. Kim, JI, K. Surewicz, P. Gambetti, and WK Surewicz. 2009. The role of glycophosphatidylinositol anchor in the amplification of the scrapie isoform of prion protein in vitro. FEBS Lett. 583:3671-3675.[CrossRef][Medline]; 21. ... Related articles - All 4 versions
[HTML] from lipidworld.comS Vascellari, S Banni, C Vacca… - Lipids in health and …, 2011 - lipidworld.com ... Taraboulos A, Scott M, Semenov A, Avrahami D, Laszlo L, Prusiner SB, Avraham D: Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapieisoform. J Cell Biol 1995, 129:121-132. ... Cached