S Ruf, O Symmons, VV Uslu, D Dolle, C Hot… - Nature genetics, 2011 - nature.com We present here a Sleeping Beauty–based transposition system that offers a simple and efficient way to investigate the regulatory architecture of mammalian chromosomes in vivo. With this system, we generated several hundred mice and embryos, each with a regulatory sensor ... All 4 versions
W Theurkauf - Developmental cell, 2011 - ncbi.nlm.nih.gov 1. Dev Cell. 2011 Aug 16;21(2):e3. Transposon Silencing of Small RNAs. Theurkauf W. ... In 2003, miRNAs and siRNAs were known to silence target mRNAs, but small RNAs had not been directly linked to transposon control. In August of that year, Aravin et al. ...
C Kettlun, DL Galvan, AL George Jr, A Kaja… - Molecular …, 2011 - nature.com The ability to direct gene delivery to a user-defined chromosomal location would greatly improve gene transfer applications. The piggyBac transposon system is a nonviral gene transfer system proven effective in a variety of cells and tissues, including human cells. We fused a highly ... All 3 versions
TK Starr, PM Scott, BM Marsh… - Proceedings of the …, 2011 - National Acad Sciences It is proposed that a progressive series of mutations and epigenetic events leads to human colorectal cancer (CRC) and metastasis. Furthermore, data from resequencing of the coding regions of human CRC suggests that a relatively large number of mutations occur in individual ... Cited by 2 - Related articles - All 3 versions
AK Cain… - Microbial Drug Resistance, 2011 - liebertonline.com The simplest form of transposon Tn 5393 carries the strA and strB genes that confer resistance to streptomycin, in addition to its transposition determinants. Tn 5393 e, made up of Tn 5393 and a second transposon, Tn 6023, was found in an IncHI2 plasmid, pSRC125 ... Related articles - All 2 versions
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