W Huang, S Ghisletti, K Saijo, M Gandhi, M Aouadi… - Nature, 2011 - nature.com Toll-like receptors (TLRs) function as initiators of inflammation through their ability to sense pathogen-associated molecular patterns and products of tissue damage 1, 2 . Transcriptional activation of many TLR-responsive genes requires an initial de-repression step in which ... Cited by 4 - Related articles - All 5 versions
YD Wang, WD Chen, D Yu, BM Forman… - Hepatology, 2011 - Wiley Online Library ... mice show more severe liver necroses and inflammation compared with wild-type (WT) mice. Activation of TGR5 by its agonist ligand inhibits the expression of inflammatory mediators in response to NF-κB activation induced by LPS in WT but not TGR5 -/- mouse liver. ... Related articles - All 2 versions
ML Allende, M Bektas, BG Lee, E Bonifacino… - Journal of Biological …, 2011 - ASBMB Sphingosine-1-phosphate (S1P) lyase catalyzes the degradation of S1P, a potent signaling lysosphingolipid. Mice with an inactive S1P lyase gene are impaired in the capacity to degrade S1P, resulting in highly elevated S1P levels. These S1P lyase-deficient mice have low ... Cited by 2 - Related articles - All 4 versions
SD Amin… - American Journal of Respiratory and Critical …, 2011 - Am Thoracic Soc Acute inflammation of the airways and surrounding tissue, either induced by inhaled environmental agents or immunological stimuli, is coordinated by many interacting mechanisms. Chemical agents diffuse throughout and bind to tissues, eliciting responses such as stress generation in ... All 3 versions
D Reid, BJ Toole, S Knox, D Talwar… - … American Journal of …, 2011 - Am Soc Nutrition 1 From the Department of Anaesthesia, Faculty of Medicine (DR, JH, and JK), the Department of Clinical Biochemistry (BJT, SK, DT, DSJO, SB, and AMW), and the Department of Surgery, Faculty of Medicine (DCM), University of Glasgow, Royal Infirmary, Glasgow, United ... Cited by 7 - Related articles - All 4 versions
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