I Topisirovic… - Cell, 2011 - Elsevier In eukaryotes, during the initiation step of translation, 40S ribosomal subunits are recruited to the mRNA by proteins known as translation initiation factors (Sonenberg and Hinnebusch, 2009). The 40S ribosome complex with associated factors navigates the mRNA 5′ ... All 2 versions
[CITATION] Signaling Pathways that Mediate Translational Control of Ribosome Recruitment to mRNA
RJO Dowling… - Regulation of Organelle and Cell …, 2011 - Academic Press Related articles
RM Voorhees, TM Schmeing, AC Kelley… - Science, 2011 - sciencemag.org Our report of the crystal structure of elongation factor Tu (EF-Tu) and aminoacyl–transfer RNA bound to the ribosome with a guanosine triphosphate (GTP) analog included a proposed mechanism of GTP hydrolysis by EF-Tu involving histidine-84. Liljas et al. summarize experimental ... Related articles
X Xie… - Cell, 2011 - Elsevier TOR is an atypical serine/threonine protein kinase conserved from yeast to mammals that forms two distinct physical and functional complexes termed TORC1 and TORC2 (Figure 1) (Wullschleger et al., 2006). TORC1, a rapamycin-sensitive complex, regulates translation, autophagy, ... Cited by 1 - Related articles - All 2 versions
X Qu, JD Wen, L Lancaster, HF Noller… - Nature, 2011 - nature.com The ribosome translates the genetic information encoded in messenger RNA into protein. Folded structures in the coding region of an mRNA represent a kinetic barrier that lowers the peptide elongation rate, as the ribosome must disrupt structures it encounters in the mRNA at its ... All 3 versions
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