A Antebi - Annual Review of Biochemistry, 2011 - annualreviews.org Sterol metabolites are critical signaling molecules that regulate metabolism, development, and homeostasis. Oxysterols, bile acids (BAs), and steroids work primarily through cognate sterol-responsive nuclear hormone receptors to control these processes through feed- ... Related articles
L Zhang, L Fairall, BT Goult, AC Calkin… - Genes & …, 2011 - genesdev.cshlp.org We previously identified the E3 ubiquitin ligase IDOL as a sterol-dependent regulator of the LDL receptor (LDLR). The molecular pathway underlying IDOL action, however, remains to be determined. Here we report the identification and biochemical and structural ... Cited by 1 - Related articles - All 2 versions
T Karasawa, A Takahashi, R Saito… - … and Vascular Biology, 2011 - Am Heart Assoc Methods and Results— Transgenic mice that overexpress SREBP-1c in the liver and SREBP-1-deficient mice were crossed with low-density lipoprotein receptor (LDLR)–deficient mice, and the plasma lipids and atherosclerosis were analyzed. Hepatic SREBP-1c ... All 3 versions
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