[HTML] from confex.comN Goardon, E Marchi, A Atzberger, L Quek… - Cancer Cell, 2011 - Elsevier The relationships between normal and leukemic stem/progenitor cells are unclear. We show that in 80% of primary human CD34+ acute myeloid leukemia (AML), two expanded populations with hemopoietic progenitor immunophenotype coexist in most patients. Both populations ... Cited by 9 - Related articles - All 4 versions
A Wada, N Kobayashi, S Asanuma… - International journal of …, 2011 - Springer Abstract A patient with acute myeloid leukemia had a relapse with a myeloid sarcoma of the stomach 32 months after allogeneic bone marrow transplantation. The patient was treated with the first donor lymphocyte infusion (DLI) and one course of induction chemotherapy. Due to ... Related articles - All 5 versions
[PDF] from stemcellres.comEJ Gudgin… - Stem Cell Research & Therapy, 2011 - Springer To date, cytogenetic abnormalities have provided most prognostic information, although up to 50% of patients have a normal karyotype [2]. In addition, over the past decade the detection of specific molecular mutations, including mutations in the NPM1 and FLT-3 genes, have ... Related articles - All 4 versions
RJ Arceci… - Childhood Leukemia, 2011 - Springer AML is a heterogeneous and complex disease that is the culmination of the interaction between genetic and epigenetic alterations in the hematopoietic progenitors, leading to dysregulation of multiple critical signal transduction pathways, resulting in hematopoietic insufficiency ... Related articles - All 2 versions
AHFM Peters… - Epigenetics and Disease, 2011 - Springer Abstract Acute leukemia is characterized by clonal expansion of hematopoietic stem and progenitor cells with blocked differentiation. Clinical and experimental evidences suggest that acute myeloid leukemia (AML) is the product of several functionally cooperating genetic alterations ... Related articles - All 4 versions
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