[HTML] from 171.66.121.246JC Lindsey, RM Hill, H Megahed… - Journal of Clinical …, 2011 - 171.66.121.246 ... 1 Of particular note, medulloblastoma is now recognized as comprising distinct moleculardisease subgroups; its primary, consistently identified subgroups are characterized by mutational activation of the Sonic Hedgehog (SHH subgroup; approximately 25% of cases) or Wnt ... Cited by 3 - Related articles - All 5 versions
[HTML] from 171.66.121.246DW Ellison, M Kocak, J Dalton… - Journal of Clinical …, 2011 - 171.66.121.246 Purpose Medulloblastomas are heterogeneous and include relatively good-prognosis tumors characterized by Wnt pathway activation, as well as those that cannot be successfully treated with conventional therapy. Developing a practical therapeutic stratification that allows ... Cited by 8 - Related articles - All 6 versions
D Kramer, R Llanos… - Metal ions and neurodegenerative …, 2011 - deakin.edu.au Eukaryotic cells prevent copper-induced, free radical damage to cell components by employing copper-binding proteins and transporters that minimize the likelihood of free copper ions existing in the cell. In the cell, copper is actively transported from the cytoplasm during the ... Cited by 3 - Related articles - Cached - All 3 versions
[CITATION] Scriver's Online Metabolic and Molecular Bases of Inherited Disease
E Valkov, A Stamp, F DiMaio… - Proceedings of the …, 2011 - National Acad Sciences Toll-like receptors (TLRs) are a family of single-pass trans- membrane proteins that mediate innate immune responses to microbial stimuli such as bacterial lipids and nonself nucleic acids (1, 2). These molecules bind directly to the extracellular domains of the receptors and ...