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Uncertainty in transfusion practice for acute upper gastrointestinal bleeding (AUGIB): implications for clinical trial design

V Jairath, B Kahan, C Dore, S Meredith, C Lweleyn… - Gut, 2011 - gut.bmj.com
Methods In preparation for a proposed UK multi-centre, cluster randomised trial of restrictive
versus liberal blood transfusion strategies in patients presenting with AUGIB we sought to
determine: (1) the key area of clinical uncertainty in RBC transfusion practice for AUGIB; ...
All 2 versions

Hospital admission database or specialist national audits for monitoring gastrointestinal bleeding? both are vital to monitoring our clinical practice

CJ Crooks, J West, SA Hearnshaw, MF Murphy… - Gut, 2011 - gut.bmj.com
Results The audit contained 7484 records of admission to hospital with UGB from England, and
5582 complete records that were included in the final analysis. Over the same time period HES
had 8495 UGB admissions from audit participating hospitals (ie, the audit captured 88.1% ...

Angiographic Embolization of Nonvariceal Upper Gastrointestinal Bleeding: Predictors of Clinical Failure

JA Lundgren, K Matsushima, FC Lynch… - The Journal of …, 2011 - journals.lww.com
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Acid Suppressants Reduce Risk of Gastrointestinal Bleeding in Patients on Antithrombotic or Anti-Inflammatory Therapy

KJ Lin, S Hernández-Díaz… - Gastroenterology, 2011 - Elsevier
The adjusted RR of UGIB associated with current use of proton pump inhibitors (PPIs) for >1
month was 0.58 (95% confidence interval [CI], 0.42–0.79) among patients that received low-dose
acetylsalicylic acid (ASA), 0.18 (0.04–0.79) for clopidogrel, 0.17 (0.04–0.76) for dual anti- ...
All 4 versions

Erythromycin Infusion or Gastric Lavage for Upper Gastrointestinal Bleeding: A Multicenter Randomized Controlled Trial

[HTML] from annemergmed.comD Pateron, E Vicaut, E Debuc, K Sahraoui… - Annals of Emergency …, 2011 - Elsevier
Two hundred fifty-three patients (181 men, mean age 61 years [SD 15 years], 84 with
cirrhosis) were randomized: 84 (erythromycin group), 85 (nasogastric group), and 84
(nasogastric-erythromycin group). Overall, there was 85% satisfactory stomach ...
Cited by 2 - Related articles - All 3 versions

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