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Trpv1 Reporter Mice Reveal Highly Restricted Brain Distribution and Functional Expression in Arteriolar Smooth Muscle Cells

[HTML] from cjb.netDJ Cavanaugh, AT Chesler, AC Jackson… - The Journal of …, 2011 - neuro.cjb.net
The heat and capsaicin receptor, TRPV1, is required for the detection of painful heat by primary
afferent pain fibers (nociceptors), but the extent to which functional TRPV1 channels are expressed
in the CNS is debated. Because previous evidence is based primarily on indirect ...
Cited by 3 - Related articles - All 5 versions

Cellular and Molecular Mechanisms of Pulmonary Vascular Smooth Muscle Cell Proliferation

T Tajsic… - Textbook of Pulmonary Vascular Disease, 2011 - Springer
Abstract Pulmonary arterial hypertension is the end result of a complex series of events termed
“vascular remodeling,” which includes proliferation of resident smooth muscle cells in the walls
of small muscular pulmonary arteries. This pro- cess leads to increased thickness of the ...
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BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways

[HTML] from rupress.orgVA de Jesus Perez, Z Ali, TP Alastalo… - The Journal of cell …, 2011 - jcb.rupress.org
We present a novel cell-signaling paradigm in which bone morphogenetic protein 2 (BMP-2)
consecutively and interdependently activates the wingless (Wnt)–β-catenin (βC) and Wnt–planar
cell polarity (PCP) signaling pathways to facilitate vascular smooth muscle motility while ...
Cited by 4 - Related articles - All 4 versions

Adventitial gene transfer of VEGFR-2 specific VEGF-E chimera induces MCP-1 expression in vascular smooth muscle cells and enhances neointimal formation

S Bhardwaj, H Roy, M Babu, M Shibuya… - Atherosclerosis, 2011 - Elsevier
The role of vascular endothelial growth factors (VEGFs) in neoitimal formation has been
controversial. VEGF receptor(R)-2 signaling pathway is crucial in bringing about the effects of
VEGFs including vasodilatation, endothelial cell migration and proliferation. In this study ...

Bone Marrow–Derived Smooth Muscle Cells Are Breaking Bad in Atherogenesis

A Schober… - Arteriosclerosis, Thrombosis, and Vascular …, 2011 - Am Heart Assoc
Vascular smooth muscle cells (SMCs) are highly specialized in contraction, thus regulating the
vascular tone. In contrast to other muscle cells, however, SMCs can reversibly undergo quite
drastic phenotypic changes in response to environmental signals. 1 Following vascular ...
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