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Ovariectomy disregulates osteoblast and osteoclast formation through the T-cell receptor CD40 ligand

[HTML] from pnas.orgJY Li, H Tawfeek, B Bedi, X Yang… - Proceedings of the …, 2011 - National Acad Sciences
The bone loss induced by ovariectomy (ovx) has been linked to increased production of osteoclastogenic
cytokines by bone marrow cells, including T cells and stromal cells (SCs). It is presently unknown
whether regulatory interactions between these lineages contribute to the effects of ovx in ...
Cited by 1 - Related articles - All 4 versions

Direct Current Potentials Applied To Titanium Surfaces Stimulate Osteoblast Differentiation

RA GITTENS, R TANNENBAUM… - 2011 - iadr.confex.com
Objectives: Electrical stimulation of titanium (Ti) implants has been used clinically to enhance
osseointegration, but the cellular and molecular mechanisms involved are not well
understood. Our objective was to develop a new in vitro system that allows electrical ...
Cached - All 2 versions

Osteoporosis in paediatric crohn's disease: influence of immune cells on proliferation of the osteoblast like cell line Saos2

G Penman, D Campbell… - Archives of Disease in …, 2011 - adc.bmj.com
Results The culture of Saos2 cells with resting PBMCs and CD4+ T cells increased their
proliferation, whereas activated cells inhibited the proliferation of Saos2 cells. These effects were
still present with the use of transwell inserts, although final cell numbers were overall ...

Biphasic effects of transforming growth factor β on bone morphogenetic protein–induced osteoblast differentiation

DJJ de Gorter, M van Dinther… - Journal of Bone and …, 2011 - Wiley Online Library
Bone morphogenetic proteins (BMPs) exert an important role in skeletal development, adult bone
homeostasis, and fracture healing and have demonstrated clinical utility for bone
regeneration. However, BMPs fall short as regenerative agents because high doses need ...
Cited by 2 - Related articles - All 3 versions

Type XII collagen regulates osteoblast polarity and communication during bone formation

Y Izu, M Sun, D Zwolanek, G Veit… - The Journal of Cell …, 2011 - jcb.rupress.org
Differentiated osteoblasts are polarized in regions of bone deposition, demonstrate extensive
cell interaction and communication, and are responsible for bone formation and quality. Type
XII collagen is a fibril-associated collagen with interrupted triple helices and has been ...
Related articles - All 2 versions

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