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Severe Encephalopathy, Lactic Acidosis, Vegetative Instability and Neuropathy with 5-Fluorouracil Treatment–Pyrimidine Degradation Defect or Beriberi?

A Rosen, A van Kuilenburg… - Case Reports in …, 2011 - content.karger.com
We present the case of a 19-year-old female with nasopharyngeal carcinoma, who received
two courses of chemotherapy with 5-fluorouracil (5-FU) in combination with folic acid and
cisplatin. Upon developing esophageal strictures in the course of her radiotherapy, she ...

DNA Mismatch repair status and colon cancer recurrence and survival in clinical trials of 5-fluorouracil-based adjuvant therapy

[HTML] from oxfordjournals.orgFA Sinicrope, NR Foster… - Journal of the …, 2011 - jnci.oxfordjournals.org
Methods We included stage II and III colon carcinoma patients (n = 2141) who were treated in
randomized trials of 5-FU-based adjuvant therapy. Tumors were analyzed for microsatellite instability
by polymerase chain reaction and/or for MMR protein expression by ...
Cited by 1 - Related articles - All 5 versions

[HTML] Calbindin 2 (CALB2) Regulates 5-Fluorouracil Sensitivity in Colorectal Cancer by Modulating the Intrinsic Apoptotic Pathway

[HTML] from plos.orgL Stevenson, WL Allen, I Proutski, G Stewart… - PloS one, 2011 - dx.plos.org
The role of the calcium binding protein, Calbindin 2 (CALB2), in regulating the response of colorectal
cancer (CRC) cells to 5-Fluorouracil (5-FU) was investigated. Real-time RT-PCR and Western
blot analysis revealed that CALB2 mRNA and protein expression were down-regulated in ...
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[HTML] A randomized phase III trial of adjuvant chemotherapy with irinotecan, leucovorin and fluorouracil versus leucovorin and fluorouracil for stage II and III colon …

[HTML] from biomedcentral.comC Papadimitriou, P Papakostas, M Karina… - BMC …, 2011 - biomedcentral.com
Colon cancer is a public health problem worldwide. Adjuvant chemotherapy after surgical resection
for stage III colon cancer has been shown to improve both progression-free and overall
survival, and is currently recommended as standard therapy. However, its value for ...
Related articles - Cached - All 7 versions

Poly (ADP-ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells

AM Huehls, JM Wagner, CJ Huntoon, L Geng… - Cancer Research, 2011 - AACR
... cells 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer Poly(ADP-ribose) polymerase
inhibition synergizes with ... Page 2. Poly(ADP-ribose) polymerase inhibition synergizes with
5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells ...
Related articles - All 2 versions

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