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Novel inflammatory mechanisms of accelerated atherosclerosis in kidney disease

S Swaminathan… - Kidney International, 2011 - nature.com
A substantial body of evidence has accumulated linking an increased incidence of cardiovascular
disease in patients with acute kidney injury (AKI), chronic kidney disease (CKD), and end-stage
renal disease (ESRD). A multitude of novel risk factors related to decreased kidney ...
All 3 versions

Oral activated charcoal adsorbent (AST-120) ameliorates extent and instability of atherosclerosis accelerated by kidney disease in apolipoprotein E-deficient mice

S Yamamoto, Y Zuo, J Ma, PG Yancey… - Nephrology Dialysis …, 2011 - ERA-EDTA
Results. Uninephrectomy and subtotal nephrectomised mice had significantly increased acceleration
of atherosclerosis. AST-120 treatment dramatically reduced the atherosclerotic burden in mice
with kidney damage, while there was no beneficial effect in sham-operated mice. The ...
Cited by 1 - Related articles - All 2 versions

Chronic Inflammatory Disorders and Accelerated Atherosclerosis: Chronic Kidney Disease

D Navab, Y Hama, S Safarpour… - Current …, 2011 - ingentaconnect.com
Abstract: Increasing evidence points to the fact that plasma HDL cholesterol levels do not always
accurately predict HDL function in- cluding reverse cholesterol transport and modulation of
inflammation. These functions appear to have evolved as part of our innate im- mune ...
Cited by 1 - Related articles - All 2 versions

Accelerated total dose infusion of low molecular weight iron dextran is safe and efficacious in chronic kidney disease patients

S Sinha, D Chiu, G Peebles, P Swoboda… - QJM, 2011 - Oxford Univ Press
Background: Low molecular weight iron dextran (LMWID) is licensed for use as a total dose infusion
(TDI) over 4–6 h. In order to improve patient convenience and cost-effectiveness of therapy, we
investigated the safety and efficacy of adopting accelerated dosing regimens and ...
Cited by 2 - Related articles - All 5 versions

… CHRONIC KIDNEY DISEASEIN VITRO AND IN VIVO VASCULAR CALCIFICATION IN CHRONIC KIDNEY DISEASE IS A PHOSPHATE-MEDIATED ACCELERATED …

K McCabe, N Shobeiri, D Beseau… - NDT …, 2011 - ndtplus.oxfordjournals.org
METHODS: Sprague Dawley rats were fed a diet containing either 0.25% adenine (CKD) or
0% adenine (control), both diets containing high phosphate (1%) and low vitamin K (0.2
mg/kg). Warfarin (0.1 mg/kg body weight/day) was administered in the drinking water of ...

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