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S Sreeja, TR Santhosh Kumar, BS Lakshmi… - The Journal of …, 2011 - Elsevier
Selective estrogen receptor modulators (SERMs) are estrogen receptor (ER) ligands exhibiting
tissue-specific agonistic or antagonistic biocharacter and are used in the hormonal therapy for
estrogen-dependent breast cancers. Pomegranate fruit has been shown to exert ...
BS Katzenellenbogen, MK Bagchi… - 2011 - ideals.illinois.edu
Estrogens are associated with the development and progression of breast cancer in addition
to their role in normal reproductive physiology, and estrogen receptors (ER) mediate the actions
of estrogen in target tissues by regulating the expression of numerous biologically ...
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B Katzenellenbogen, A Nardulli, D Shapiro… - 2011 - ideals.illinois.edu
Repressor of Estrogen Receptor Activity (REA) is an evolutionarily conserved protein with established
roles in multiple, essential cellular processes including transcription, mitochondrial biogenesis
and replicative senescence. Previous reports suggest that REA is a multifunctional ...
Cached - All 2 versions
AE Richardson - 2011 - gradworks.umi.com
Basal-like BC (BLBC) is a sub-group of estrogen-independent tumors that have a very aggressive
clinical behavior and are resistant to hormone-based therapy resulting in reduced disease-free
survival period and increasing the mortality of breast cancer (BC) patients. Our BC ...
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TW Miller, JM Balko, EM Fox, Z Ghazoui… - Cancer Discovery, 2011 - AACR
Most estrogen receptor α (ER)-positive breast cancers initially respond to antiestrogens, but many
eventually become estrogen-independent and recur. We identified an estrogen-independent
role for ER and the CDK4/Rb/E2F transcriptional axis in the hormone-independent growth ...

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