S Sreeja, TR Santhosh Kumar, BS Lakshmi… - The Journal of …, 2011 - Elsevier Selective estrogen receptor modulators (SERMs) are estrogen receptor (ER) ligands exhibiting tissue-specific agonistic or antagonistic biocharacter and are used in the hormonal therapy for estrogen-dependent breast cancers. Pomegranate fruit has been shown to exert ...
BS Katzenellenbogen, MK Bagchi… - 2011 - ideals.illinois.edu Estrogens are associated with the development and progression of breast cancer in addition to their role in normal reproductive physiology, and estrogen receptors (ER) mediate the actions of estrogen in target tissues by regulating the expression of numerous biologically ... Cached - All 2 versions
B Katzenellenbogen, A Nardulli, D Shapiro… - 2011 - ideals.illinois.edu Repressor of Estrogen Receptor Activity (REA) is an evolutionarily conserved protein with established roles in multiple, essential cellular processes including transcription, mitochondrial biogenesis and replicative senescence. Previous reports suggest that REA is a multifunctional ... Cached - All 2 versions
AE Richardson - 2011 - gradworks.umi.com Basal-like BC (BLBC) is a sub-group of estrogen-independent tumors that have a very aggressive clinical behavior and are resistant to hormone-based therapy resulting in reduced disease-free survival period and increasing the mortality of breast cancer (BC) patients. Our BC ... Cached
TW Miller, JM Balko, EM Fox, Z Ghazoui… - Cancer Discovery, 2011 - AACR Most estrogen receptor α (ER)-positive breast cancers initially respond to antiestrogens, but many eventually become estrogen-independent and recur. We identified an estrogen-independent role for ER and the CDK4/Rb/E2F transcriptional axis in the hormone-independent growth ...
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